Research Platforms' Performance Reports TMB 2015-2017 | Page 23

Disease Module Identification and Validation:
The comprehensive data generated is subjected to gene
ontology analysis using tools like DAVID and Blast2go to
refine and categorize the interactions into different biological
processes like transcription, translation, replication and
signaling pathways. Mathematical modeling along with
reported and validated host-virus interactions shall be used
to predict key components that can be further assessed
by introducing perturbations and monitoring the effects of
these changes on the network as a whole thereby enabling
us to identify NP-specific disease modules i.e. a group
of