Effect of tulasi on incidence and mortality. In a Korean study,
prostate cancer:
As of 2011, prostate
cancer is the second
most frequently diagnosed cancer and the
sixth leading cause of
cancer death in males
worldwide [9]. In a
study done in USA, flavonoid vicenin-2 (VCN2), an active constituent of tulasi, effectively
induces anti-proliferative,
anti-angiogenic and pro-apoptotic
effect in prostate cancer
cells. This study provided strong evidence
that VCN-2 is effective
against prostate cancer
progression in androgen-independent prostate cancer. [10]
Effect of tulasi on
lung cancer:
Worldwide, lung cancer is the most common
cancer in terms of both
results
demonstrate
that ethanol extracts
of Ocimum sanctum
(EEOS) induces apoptosis in human nonsmall cell lung carcinoma (NSCLC) A549 cells
via a mitochondria caspase-dependent pathway and inhibits the in
vivo growth of Lewis
lung carcinoma (LLC)
animal model, suggesting that EEOS can be
applied to lung carcinoma as a chemo-preventive candidate [11].
34
Effect of tulasi on
other cancers:
In an Indian study,
tulasi leaves significantly decreased the
incidence of both B[a]
P-induced
neoplasia
and 3’MeDAB-induced
hepatomas in mice
[12].
In
another Indian
s t u d y,
administration of
ethanolic
tulasi leaf
extract
reduced
the incidence of
N-methylN ’ - n i t r o N nitrosoguanidine
(MNNG) -induced gastric carcinomas in rats
[13].