Ispectrum Magazine Ispectrum Magazine #10 | Page 34

Further confirming this, an extract from tulasi is found to protect one from harmful nuclear radiations. The active constituents of tulasi are now being turned into a drug at a Gujarat facility. The drug could be a boon for cancer patients to alleviate the side effects of radiotherapy treatment. The human clinical trials are nearing completion at the Advanced Center for Treatment Research and Education at the Tata Memorial Centre in Mumbai. [5] Effect of tulasi on various cancers Chandrakanth Emani, assistant professor of plant molecular biology at Western Kentucky University-Owensboro (WKU-O) in the US said that the tulasi plant could serve as a storehouse of anti-cancerous compounds like eugenol [6]. Effect of tulasi on pancreatic cancer: Pancreatic cancer is one of most aggressive cancers and has one of the highest fatality rates among all cancers (5-year survival is estimated as less than 5%) [7]. Scientists have shown in vitro that extracts of tulasi leaves inhibit the proliferation, migration, invasion, 33 and induce apoptosis of pancreatic cancer cells. The expression of genes that promote the proliferation, migration and invasion of pancreatic cancer cells including activated ERK-1/2, FAK, and p65 (subunit of NF-κB), was down regulated in pancreatic cancer cells Y