Ispectrum Magazine Ispectrum Magazine #10 | Page 33

prevented chemicalinduced skin, liver, oral, and lung cancers by increasing the antioxidant activity, altering the gene expressions, inducing apoptosis, and inhibiting angiogenesis and metastasis. Eugenol, rosmarinic acid, apigenin, and carnosic acid are also shown to prevent radiationinduced DNA damage [2]. Another study confirms the possible radio-protective effect of tulasi against high-dose (131) Iodine exposure [3]. In a study by Monga J et al, the 50% alcoholic aqueous extract of different species of tulasi, was admini s t e r e d orally in mice and resulted 32 in significant reduction in tumor volume, increase in average body weight, and the survival rate of mice. The various extracts showed modulatory influence against lethal irradiation doses of gamma radiation in terms of radiationinduced chromosomal damage, while at the same time induced an increase in reduced glutathione level (an antioxidant) and GST activi t y [4].