Anti-cancer mechanisms of tulasi
In a study done by
Industrial Toxicology
Research
Centre,
Lucknow, on the protective effect of tulasi,
effects of the alcoholic
extract of the leaves
of tulasi on 3-methylcholanthrene (MCA),
7,12-dimethylbenzan-
thracene (DMBA) and
aflatoxin B1 (AFB1)
induced skin tumorigenesis in a mouse model
were investigated. It
was concluded that leaf
extract of tulasi provides protection against
chemical carcinogenesis in one or more
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of the following mechanisms: (i) by acting
as an antioxidant; (ii)
by modulating phase I
and II enzymes; (iii) by
exhibiting anti-proliferative activity [14]