iS Skin Source 2022 Q4 2022 Q4 | Page 58

PRF & PRP : The Gold Standard of Blood Concentrate for Facial Aesthetics | by Kendra Clark
extracellular matrix ( ECM ). PRP does so by increasing certain skin enzymes that remove damaged components , promote collagen synthesis , and support new tissue growth .
These molecular effects benefit the integrity and appearance of the skin visible to the naked eye . PRP treatments are essential for those who are concerned with loss of elasticity and volume . PRP is highly effective when used for delicate under-eye tissue that

Of particular interest , platelet concentrates can also reverse signs of aging , as well as initiate , improve , and accelerate healing . may not be suitable for laser therapy . PRP is also used to increase the overall structural integrity of the skin , particularly sun-damaged skin .

Platelet-Rich Fibrin – PRF
PRF is a second-generation platelet concentrate that aims to address varied limitations of PRP . Like PRP , it is autologous and prepared from a patient ’ s blood . Different from PRP , PRF undergoes centrifugation in one step and does not use anticoagulants . Because of this different process , PRF contains more platelets than PRP . It also contains growth factors , red cells , leukocytes , and an extracellular fibrin matrix 3 . Likewise , PRF can stimulate cell growth , collagen synthesis , and gene expression within the skin 4 .
PRF can be produced in either a liquid or solid gel form , depending on the centrifuge process . When producing
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