the fluid form , the blood product is centrifuged at a lower speed and duration to form a liquid . Facial aesthetics can use the injectable liquid form of PRF , known as I-PRF . The preparation of PRF allows for the gradual release of growth factors over time 3 .
To assess the efficacy of PRF in skin rejuvenation , one study investigated how PRF affected nasolabial folds . The average wrinkle assessment scale score decreased by two points immediately after administration . Though the score increased after a week , the improved score was sustained through 12 weeks post-treatment 4 . Other studies have demonstrated the effects of I-PRF in improving skin appearance and patient satisfaction 3 .
Choosing a Procedure
Both PRP and PRF require blood to be taken from the patient . PRP requires more blood to be taken than PRF . Both products require the whole blood sample to be placed into a centrifuge , where the blood is then processed to help separate the blood into distinct layers . Platelet-rich plasma is spun at a higher speed , which effectively causes all the heavier cells in the blood , such as white blood cells and stem cells , to collect in the bottom part of the test tube and allows the lighter platelets and plasma to collect in the top part of the test tube .
PRP and PRF are two safe and effective concentrates , providing a natural option for those looking to improve overall skin integrity […]
The platelets and plasma are then collected from the upper part of the test tube and injected into the region with tissue damage . However , newer research is showing that a platelet product that has an even higher concentration of platelets , as well as a concentration of some white blood cells and stem cells , is even more effective than traditional platelet-rich plasma . With this new information , platelet-rich fibrin was created .
The PRF product is spun at a slower speed so that the layers of the blood do not separate as distinctly . This allows some of the white blood cells and stem cells to remain within the platelet layer that is collected for treatment . Thus , there are more healing factors within PRF than is typically seen in PRP . In addition , the lower spin speed causes