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Human herpes virus 3
Human herpes virus 3 (HHV3) is also called vermicelli-zoster virus. HHV3
causes chickenpox. It can also cause a recurrent virus infection of the skin,
which is called herpes zoster or shingles.
Shingles occurs when dormant vermicelli-zoster virus from an initial bout of
chickenpox becomes reactivated. Like its close relative, HHV1, herpes zoster
likes to infect skin cells and nerve cells. This virus may also recur along nerve
fibre pathways, causing multiple sores where nerve fibres end on skin cells.
Because an entire group of nerve cells is often affected, shingles is generally
much more severe than a recurrence of herpes simplex. The lesions
generally appear in a band-like or belt-like pattern occurring on one side of
the body and are often accompanied by itching, tingling, or even severe pain.
Healing usually occurs in 2 to 4 weeks, and scars may remain. Post herpetic
neuralgia is a complication of shingles where the pain associated with the
infection can persist for months and even years. Most people who experience
shingles once do not experience it again.