Frontshop Nov '13 november 2013 | Página 22

HEARTBURN A burning issue S By Marjolein Bench, BPharm IMM ymptoms of heartburn include a burning pain in the chest that usually occurs after eating and may occur at night and pain that worsens when lying down or bending over. The pain often rises in the chest and may radiate to the neck, throat, or angle of the jaw. Heartburn is usually associated with regurgitation of gastric acid (gastric or acid reflux) which is the major symptom of gastro-oesophageal reflux disease (GORD). It may also be a symptom of ischemic heart disease, though this is true for only 0.6% of those experiencing heartburn. Reflux occurs when the ring-shaped muscle that normally prevents the contents of the stomach from flowing back into the oesophagus (lower oesophageal sphincter) does not function properly. Stomach acid and enzymes flow backward from the stomach into the oesophagus, causing inflammation and pain in the oesophagus. The most typical symptom is heartburn. The stomach lining protects the stomach from the effects of its own acid. Because the oesophagus lacks a similar protective lining, stomach acid and enzymes that flow backward (reflux) into the oesophagus, routinely cause symptoms and in some cases damage. When a person is standing or sitting, gravity helps to prevent the reflux of stomach contents into the oesophagus, which explains why reflux can worsen when a person is lying down. Reflux is also more likely to occur soon after meals, when the volume and acidity of contents in the stomach are higher and the sphincter is less likely to work properly. Factors contributing to reflux include: • • • • • • • 22 | NOVEMBER 2013 FrontShop weight gain fatty foods chocolate caffeinated and carbonated beverages alcohol tobacco smoking certain drugs.