RECENT RESEARCH
function tests along with incidence of secondary complications , and time to return to a normal routine was done .
Results : One-week intervention of AYUSH 64 helped to recover from ILI symptoms with reduced frequency of usage of acetaminophen and antihistaminic . The intervention was safe on hematology and biochemical parameters . No serious adverse effects were observed during the study .
Conclusion : AYUSH 64 along-with standard care in ILI is safe and efficacious and this may be used in other viral infections with pyrexia as add-on to standard care for early recovery and better outcome .
Complementary medicine
Kim T-H , Jeon SR , Kang JW , Kwon S . Complementary and Alternative Medicine for Long COVID : Scoping Review and Bibliometric Analysis . Evid Based Complement Alternat Med . 2022 ; 7303393 . doi : 10.1155 / 2022 / 7303393
Prolonged symptoms after the clearance of acute coronavirus disease 2019 ( COVID-19 ) infection , termed long COVID , are an emerging threat to the post-COVID-19 era . Complementary and alternative medicine ( CAM ) interventions may play a significant role in the management of long COVID . The present study aimed to identify published studies on the use of CAM interventions for long COVID and provide an overview of the research status using bibliometric analysis . The present scoping review searched MEDLINE , Embase , and Cochrane Library from inception until November 2021 and identified published studies on CAM interventions for long COVID . A narrative analysis of the study types and effectiveness and safety of the CAM interventions are presented and a bibliometric analysis of citation information and references of the included publications were analyzed using the Bibliometrix package for R . An electronic database search identified 16 publications ( 2 clinical studies and 14 study protocols of systematic reviews or clinical studies ) that were included in the present study . Dyspnea or pulmonary dysfunction , quality of life , olfactory dysfunction , and psychological symptoms after COVID-19 infection were assessed in the included publications . The two clinical studies suggested that Chinese herbal medications were effective in relieving symptoms of pulmonary dysfunction . Bibliometric analysis revealed the current trend of research publication in this area was driven by study protocols written by Chinese , Korean , and Indian authors . Thus , the present scoping review and bibliometric analysis revealed that there are few studies published about the use of CAM for long COVID and long-term management for COVID-19 survivors . Original studies on CAM interventions , including randomized controlled trials and systematic reviews , are required to actively support evidence for their use in the management of long COVID . PROSPERO registration : this trial is registered with CRD42021281526
Herbal medicine
Vysochyna I , Kramarchuk V , Yashkina T . Post-viral fatigue syndrome in children : does it need to be treated ? Child ’ s Health . 2022 ; 16 ( 6 ), 425 – 434 . https :// doi . org / 10.22141 / 2224- 0551.16.6.2021.241720
Acute respiratory viral diseases continue to dominate among the causes for seeking medical help . In the pediatric population , about 60 % of cases have a recurrent course , which in turn often leads to the development of post-viral asthenic syndrome . In such children , one can find rapid fatigability , attention disorders and inability to concentrate , impaired information processing , emotional lability , and sleep disorders . All this disrupts the usual way of life of both the child and his relatives that undoubtedly requires the treatment of this condition and complete restoration of the state of the body after episodes of acute respiratory diseases . Phytotherapy has found its place in the management of children with post-viral asthenia due to the polyvalence of the pharmacological action , proven efficiency , safety of longterm therapy with phytopreparations and economic attractiveness for the majority of the population . In modern realities , phytotherapy is used as a reductive therapy , which makes up for the lack of products of intermediate metabolism in the body ; as detoxification therapy that provides adsorption or chemical binding of exo- and endotoxins , increasing the body ’ s resistance to them and stimulating the excretory systems . It is important to use the neurotropic , immunotropic , hormone-like action of biologically active substances of plants ; natural compounds , actively modifying the functions of regulatory systems , have prospects in the treatment of complex diseases . Analysis of the search databases PubMed , Web of Science , Scopus , Google Scholar , RSCI , Index Copernicus , BMJ , MEDLINE on the possibility of use , efficacy and safety of phytocomponents of Alleva in children of different ages with symptoms of post-viral asthenia allowed to ensure the application of this drug to control manifestations of asthenic syndrome . The article analyzes the options for correcting childhood asthenia with dry concentrates of linden flowers , lemon balm , chamomile , extracts of passionflower , hop , orange tree and lavender .
Karosanidze I , Kiladze U , Kirtadze N , Giorgadze M , Amashukeli N , Parulava N , Iluridze N , Kikabidze N , Gudavadze N , Gelashvili L , Koberidze V , Gigashvili E , Jajanidze N , Latsabidze N , Mamageishvili N , Shengelia R , Hovhannisyan A , Panossian A . Efficacy of Adaptogens in Patients with Long COVID-19 : A Randomized , Quadruple-Blind , Placebo- Controlled Trial . Pharmaceuticals ( Basel ). 2022 ; 11 ; 15 ( 3 ): 345 . doi : 10.3390 / ph15030345 .
Currently , no effective treatment of comorbid complications or COVID-19 long-haulers during convalescence is known . This randomized , quadrupleblind , placebo-controlled trial aimed to assess the efficacy of adaptogens on the recovery of patients with Long COVID symptoms . One hundred patients with confirmed positive SARS-CoV-2 test , discharged from COVID Hotel isolation , Intensive Care Unit ( ICU ), or Online Clinics , and who experienced at least three of nine Long COVID symptoms ( fatigue , headache , respiratory
162 | vol28 | no3 | JATMS