Annual Review 2017 | Page 13

Dengue and dengue-like illness surveillance in Johor, Malaysia Dengue fever affects 50-100 million people annually, resulting in around 200,000 deaths. Nearly 75% of the world’s population exposed to dengue lives in the Asia-Pacific region. This surveillance study aims to recruit 400 adult patients presenting with dengue and dengue-like illnesses at the Mahmoodiah Clinic, Johor Bahru. The study will contribute to a greater understanding of dengue-like illnesses in light of different strains of dengue virus serotypes in Southeast Asia. It will provide health authorities with guidance on the rates of other common infections such as influenza, and of emerging infections like zika and chikungunya. Researcher Funding Agency Associate Professor Nor'azim Mohd Yunos United States Naval Medical Research Center – Asia (Singapore) Collaborator Ministry of Health Malaysia The Clinical Effects of Tocotrienols: A systematic review Tocotrienols have gained global attention, owing to their distinctive pharmacological properties compared to tocopherol. However, it has been challenging for global health authorities to recognise tocotrienols as part of the functional vitamin E family, as mixed results were obtained from clinical studies. In order to address issues raised by health authorities, this systematic review aims to summarise the clinical effects of tocotrienols. Results from the study will assist in tocotrienol product development in terms of appropriate dosages and formulations, and serve as a reference point to recommend future research directions. Researchers • • • • Professor Nathorn Chaiyakunapruk Dr Chuah Lay Hong Dr Tahir Mehmood Khan Co-researchers from Malaysia Palm Oil Board and Mahasarakham University Funding Agency Malaysia Palm Oil Board Research into current trends in low-cost automation technologies in the global textile industry Neighbouring countries with cheaper labour costs are providing stiff competition to Malaysia’s textile and apparel manufacturing industry. A solution to remain competitive is to move towards automation, which increases productivity while reducing dependency on manual labour. A team of academics and students from the Mechatronics Engineering discipline investigated trends and automation solutions that are available to the textile/apparel industry worldwide. Based on this analysis, the team provided recommendations on low-cost automation for the local industry. The findings contributed a chapter on Low-Cost Automation in the Labour Saving Devices handbook. Researcher Funding Agency Associate Professor Tan Chee Pin Malaysian Textile and Apparel Centre Development and calibration of a budget impact model for Aloxi in chemotherapy-induced nausea and vomiting Nausea and vomiting can cause considerable distress and discomfort to patients undergoing chemotherapy, radiotherapy or surgery. Several classes of drugs have been used to combat these side effects and evidence suggests that the 5HT3 receptor antagonist is effective. This study aims to review existing evidences on the effectiveness of palonosetron. Results will be used to inform decision-making within the publicly funded health and social care system in Malaysia, ensuring that resources are used in the most benefic ial manner in order to improve public health and welfare. Researcher Funding Agency Dr Shaun Lee Wen Huey Mundipharma Pharmaceuticals Sdn Bhd 12