xvi Contents
Toxicity Acute toxicity Chronic toxicity Diagnosis Treatment Warnings Concluding remarks and future directions References
41. Fipronil
Ramesh C. Gupta and Arturo Anadón
Introduction Background Toxicokinetics Mechanism of action Toxicity Laboratory animals Dogs and cats Domestic animals Birds and fish Diagnosis Treatment Concluding remarks and future directions References
42. Macrocyclic lactone endectocides
Laura Stern, Sharon M. Gwaltney-Brant, Camille DeClementi, and Ramesh C Gupta
Introduction
Background Ivermectin Abamectin Selamectin Doramectin Eprinomectin Milbemycin Moxidectin Pharmacokinetics / toxicokinetics Mechanism of action Toxicity Toxicity data Clinical effects Diagnosis
Treatment Decontamination Monitoring and therapy Concluding remarks and future directions References
532 532 534 535 535 535 535 535
Section G Herbicides and fungicides
43. Toxicity of herbicides
Ramesh C. Gupta and Pawan K. Gupta
Introduction Background Toxicokinetics
Mechanism of action Toxicity
Inorganic herbicides and organic
arsenicals 539 Phenoxy acid derivatives
539 Bipyridyl derivatives 540 Ureas and thioureas 541 Phosphonomethyl amino acids or inhibitors
541 of aromatic acid biosynthesis 541 Protoporphyrinogen oxidase inhibitors 542 Triazines and triazoles 543 Substituted anilines 543 Amides and acetamides 543 Dinitrophenol compounds
543 Triazolopyrimidine herbicides Imidazolines
543 Benzoic acids 543 Carbamates, thiocarbamates and dithiocarbamate compounds
Others Endocrine disruption Treatment Concluding remarks 547 directions 550 References 550
550 44.
550 550
Toxicity of fungicides
Ramesh C. Gupta and Pawan K. Gupta
551 |
Introduction |
551 |
Background |
551 |
Toxicokinetics |
551 |
Mechanism of action |
553 |
Toxicity |
554 |
Inorganic fungicides |
554 |
Metallic fungicides |
554 |
Halogenated substituted monocyclic |
557 |
aromatics |
557 |
Chloroalkylthiodicarboximides |
557 |
( phthalimides) |
557 |
Anilinopyrimidines |
Carbamic acid derivatives |
558 |
Benzimidazoles |
558 |
Conazoles |
565 565 566 568 569
570 570 571 571
572 573 573 573 574 574 574 574 575
575 575 575 576
576 576
581 581 582 584 585 586 587
587
588 588 588 589
589