Reproductive toxicity
Specific target organ toxicity - single exposure
Specific target organ toxicity - repeated exposure
In laboratory animal studies , effects on reproduction have been seen only at doses that produced significant toxicity to the parent animals . ( Spinosad ) Based on available data , the classification criteria are not met .
Due to lack of data the classification is not possible .
In animals , has been shown to cause vacuolation of cells in liver , kidney , and bone tissues and changes in blood and serum biochemistry . Dose levels producing these effects were many times higher than any dose levels expected from exposure due to use . ( Spinosad ) Based on available data , the classification criteria are not met .
Aspiration hazard No aspiration toxicity classification ( spinosad )
12 . Ecological information
Ecotoxicity Very toxic to aquatic life with long lasting effects . Components Milbemycin A3 5-oxime ( CAS 114177-14-9 ) Aquatic Acute Fish
Spinosad ( CAS 168316-95-8 ) Aquatic
LC50
Species
Carp ( Cyprinus carpio )
Test results
0.059 mg / l , 48 hours
Algae EC50 Algae 0.107 mg / l Navicula sp .
Crustacea Fish
Persistence and degradability Bioaccumulative potential Mobility in soil
EC50 LC50
Green algae ( Selenastrum capricornutum )
Daphnia
Rainbow trout , donaldson trout ( Oncorhynchus mykiss )
Sunfish ( Lepomis )
No data is available on the degradability of this product . No data available for this product . Not available . Other adverse effects Not available .
13 . Disposal considerations
Disposal methods / information
14 . Transport information
General information
105.5 ppm ( currently known as Pseudokirchneriella subcapitata )
92.7 mg / l , 48 h 30 mg / l , 96 h
5.94 mg / l , 96 h
Dispose of contents / container in accordance with local / regional / national / international regulations . Do not allow this material to drain into sewers / water supplies .
Effective January 1 , 2015 by Special Provision , UN3077 and UN3082 when packaged in inner packages of 5L / 5 KG or less are not subject to the dangerous goods regulations .
ADG |
UN number |
3077 |
UN proper shipping name |
Environmentally hazardous substance , solid , n . o . s .( SPINOSAD , Milbemycin Oxime ) |
Transport hazard class ( es ) |
Class |
9 |
Subsidiary risk |
- |
Packing group |
III |
Environmental hazards |
Yes |
Hazchem Code |
2Z |
|
Special precautions for user
Not available .
|
Not classified as dangerous goods when transported by road or rail in packaging or receptacles not exceeding 500 kg ( L ) |
according to ADG 7 SP AU01 . |
RID |
UN number |
3077 |
UN proper shipping name |
Environmentally hazardous substance , solid , n . o . s .( SPINOSAD , MILBEMYCIN OXIME ) |
Transport hazard class ( es ) |
Class |
9 |
Subsidiary risk |
- |
Material name : Comfortis Plus ( Spinosad + Milbemycin Oxime ) Chewable Tablets for Dogs 4.6 - 9 KG 4510
SDS AUSTRALIA
5 / 8