Vet Lines MSDS Comfortis Plus 4.6-9kg MSDS | Page 4

Explosive limit – upper (%) No data available. Vapour pressure No data available. Vapour density No data available. Relative density No data available. Solubility(ies) Solubility (water) No data available. Partition coefficient (n-octanol/water) No data available. Auto-ignition temperature No data available. Decomposition temperature No data available. Viscosity No data available. Other physical and chemical parameters No data available. Density Explosive properties Not explosive Oxidising properties The substance or mixture is not classified as oxidizing. Potential for dust explosion No data available. 10. Stability and reactivity Reactivity Not water reactive. Chemical stability Material is stable under normal conditions. Possibility of hazardous reactions Hazardous polymerisation does not occur. Conditions to avoid None known. Incompatible materials Strong oxidising agents. Hazardous decomposition products Fire or excessive heat may produce hazardous decomposition products. 11. Toxicological information Acute toxicity Components Based on available data, the classification criteria are not met. Species Test results Dermal LD Rabbit > 5000 mg/kg Inhalation LC50 Rat > 5180 mg/m3, 4 hours Oral LD Rat > 5000 mg/kg (female) LD50 Rat 4444 mg/kg (male) Spinosad (CAS 168316-95-8) Acute Skin corrosion/irritation Serious eye damage/irritation Rabbit: No irritation (Spinosad) Based on available data, the classification criteria are not met. Rabbit: Slight irritation. (Spinosad) Based on available data, the classification criteria are not met. Respiratory or skin sensitisation Due to lack of data the classification is not possible. Respiratory sensitisation Skin sensitisation Germ cell mutagenicity Carcinogenicity Guinea pig: Not a skin sensitiser. (Spinosad) Based on available data, the classification criteria are not met. Result in genetic toxicity assays (in vitro and in vivo): Negative (Spinosad) Based on available data, the classification criteria are not met. Animal testing did not show any carcinogenic effects. (Spinosad) Based on available data, the classification criteria are not met. Material name: Comfortis Plus (Spinosad + Milbemycin Oxime) Chewable Tablets for Dogs 4.6 - 9 KG 4510 SDS AUSTRALIA 4 / 8