UALGORITMO 1 Ualgoritmo N1 2019 | Page 19

Volume: 1 Número: 3 outubro 2019 Rejuvenescer células “velhas”, é possível? Autores: José Bragança e João M.A. Santos Afilições: Departamento de Ciências Biomédicas e Medicina, Centro de Investigação em BioMedicina-CBMR, Universidade do Algarve Revisão: Escola: ES Pinheiro e Rosa, Faro Alunos: Catalina Botnaru, Diogo Lourenço, Inês Borges, Janine Ferro, Luena Marques, Maximilian Kaiser, Pedro Jesus, Rodrigo Fernandes, Rúben Gonçalves e Sofia Ramalho ABSTRACT: The possibility of reprogramming differentiated adult cells which are limited in their functions, into cells capable of generating all cell types of the adult organism has opened new horizons in regenerative medicine. However, for a safe use of reprogrammed cells in new clinical applications, the reprogramming process remains to be improved. We have showed that the use of the protein Cited2 in during the reprogramming procedure increases the efficiency and homogenizes the process. 17