The mazda pharma Guide 15th Julu - 21st july 2013 | Page 76

�MACHINERY ARTICLE

industry and will bring value to all practices, both
Philips ' AlluraClarity was commercially
international pharmaceutical company, SK
large and small. The addition of Mentor ' s breast
introduced outside the US in mid-2012, and since
Biopharmaceuticals, and the Korea-based
aesthetic portfolio is truly exciting news for our
then more than 200 systems have been ordered.
emerging biotech, AriBio, have entered into a
customers and we are excited about future
With this important milestone of FDA clearance,
collaboration agreement for SK
iterations of the programme to come."
the system can now be marketed in the world ' s
Biopharmaceuticals ' novel new small molecule
Valeant Pharmaceuticals International,
largest healthcare market.
SKL-G that is being developed for the treatment of
Inc. is a multinational specialty pharmaceutical
PHARMACEUTICAL PACKAGING
glaucoma.
company that develops, manufactures and markets
PRODUCTS SUPPLIER, CHESAPEAKE:
The
Dr. Christopher Gallen, CEO and
a broad range of pharmaceutical products primarily
Carlyle Group, a global alternative asset manager,
president of SK Biopharmaceuticals, said,“ While
in the areas of dermatology, neurology and
has acquired Chesapeake, one of the largest global
focused on the disorders and mechanisms of the
branded generics.
suppliers of value-added paper-based packaging
nervous system, the powerful SK
ROYAL PHILIPS ' ALLURACLARITY LIVE
products and services from Irving Place Capital
Biopharmaceuticals Third Wave discovery
IMAGE GUIDANCE SYSTEM:
Royal Philips
and funds managed by Oaktree Capital
platform creates compounds that are also relevant
has received 510( k) clearance from the US Food
Management.
to diseases in other body systems, in this case, the
and Drug Administration( FDA) to market its
Capital for this investment will come
eye. Through this agreement, both companies can
innovative AlluraClarity live image guidance
from Carlyle Europe Partners III L. P., a € 5.3
realize a creative drug development process by
system in the US.
billion fund that makes mid- and large-cap
sharing R & D capabilities, know-how, and
In close collaboration with leading clinicians in the
investments. Further terms of the investment were
experiences.”
field of minimally-invasive medicine, Philips has
not disclosed.
Dr. Soo-Hyun Sung, CEO and president
been driving innovation in interventional imaging
Headquartered in Nottingham, UK, and
of AriBio, said,“ This agreement recognizes
for more than 50 years, helping to guide
with nearly 5,000 employees across 38 sites in 9
AriBio ' s capabilities in drug discovery and
procedures such as the catheter-based treatment of
countries, Chesapeake is a high quality and
development for ophthalmologic disorders. Also, it
obstructed coronary arteries, brain aneurysms,
premium producer of paper-based leaflets, labels
is an excellent example of collaboration between a
heart rhythm disorders and defective heart valves
and cartons, primarily for the pharmaceutical,
medium-sized venture company and a major
( heart valve replacement).
confectionery and premium drinks markets for a
conglomerate.”
Philips ' AlluraClarity system with its
blue-chip client base. Chesapeake has grown
SK Biopharmaceuticals has discovered
powerful ClarityIQ technology provides high
significantly in recent years to produce revenues of
this innovative drug candidate and has evaluated
quality imaging for a comprehensive range of
€ 580 million in 2012.
its potential in animal models with AriBio since
clinical procedures, achieving excellent visibility
Eric Kump, managing director Carlyle
2012. The animal experiments showed that SKL-G
at low X-ray dose levels for patients of all sizes. To
Europe Partners, said:“ Chesapeake is a strong
successfully prevented optic nerve cell death and,
reflect the cost pressures that modern hospitals and
business focused on attractive growth markets.
in addition, lowered intraocular pressure that is one
health systems face, ClarityIQ technology will also
The management team has delivered sustained
of the major causes of glaucoma.
be available as an upgrade for the majority of
growth and significantly strengthened the company
Most currently-marketed glaucoma drugs have
Philips ' installed base of monoplane and biplane
in recent years. We look forward to partnering
only symptomatic treatment effects, lowering
interventional X-ray systems.
with them to further develop the company ' s
intraocular pressure, but they fail to address the
“ All patients treated via X-ray guided
international footprint and to invest in delivering
disease process itself, eventually resulting in
interventions benefit from the advantage of low
industry leading products and services. We believe
blindness. Thus fundamental therapies that can
radiation exposure, but it is especially important
the combination of Carlyle ' s global presence and
prevent optic nerve cell death represent an
when you are treating patients who have to
network and the strength of the company ' s existing
enormous unmet medical need.
undergo lengthy and complex procedures,” said
footprint and customer relationships will help drive
Because the evaluation results fully
Dr. Marco van Strijen, interventional radiologist at
significant growth and new market opportunities in
supported the competitive advantage of SKL-G
the St. Antonius Hospital Utrecht / Nieuwegein, the
the coming years.”
over existing therapies, the decision was made to
Netherlands.“ We have been using Philips '
Mike Cheetham, chief executive officer of
form a strategic alliance for preclinical and clinical
AlluraClarity system for more than a year now and
Chesapeake commented:“ We are delighted to have
development.
have really grown to appreciate the low dose
Carlyle working with us as we continue building
SK biopharmaceuticals and AriBio have
settings. This technology is making a difference
on the strong reputation we have earned for our
agreed to complete preclinical development shortly
where it really matters."
high quality products and services. Carlyle ' s
and then start clinical trials following an
“ The transition from highly invasive
backing will support our aspirations to build upon
Investigational New Drug( IND) application to US
surgical procedures to minimally-invasive image-
our strong investments over the past three years as
FDA. They are also considering various strategic
guided therapies, with all their intrinsic patient
we further grow and develop our business. This
options for partnering and commercialization.
benefits, is a transformation in the delivery of
collaboration will allow us to respond effectively
The market size for glaucoma treatments is
healthcare that is rapidly accelerating around the
to new business opportunities as we look to further
estimated to be over $ 3 billion in 2010, and the
globe,” said Gene Saragnese, CEO Imaging
align our business with our customers ' global
market might be quite larger if other
Systems at Philips Healthcare.“ It is an area where
requirements.”
ophthalmology disorders such as age-related
technology innovation and procedure innovation
The Carlyle Group is a global alternative
macular degeneration are considered. SK
go hand in hand. AlluraClarity is a perfect example
asset manager with $ 176 billion of assets under
Biopharmaceuticals is a global pharmaceutical
of how Philips ' close collaboration with clinical
management across 114 funds and 76 fund of
company that was spun out in April 2011 from SK
partners has combined these two areas of
funds vehicles as of March 31, 2013.
Holdings, the third-largest conglomerate in South
innovation to facilitate more advanced treatment
Chesapeake is a leading international
Korea. SK Biopharmaceuticals focuses on the
while at the same time managing radiation dose.”
supplier of consumer packaging. The business,
discovery and development of new drugs for the
AlluraClarity ' s low X-ray dose settings
focused on quality and innovation, supplies
treatment of central nervous system disorders.
are a radical new development in the healthcare
paperboard products to the pharmaceutical and
AriBio is one of the emerging biotech
industry that will help clinicians to better manage
premium consumer goods markets. The company
companies in Korea specializing in new drug
their patients ' and their own exposure to X-ray
produces a full range of folding cartons, leaflets
development in various areas with high unmet
radiation. This achievement is the result of a multi-
and labels at 37 locations in Asia, Europe and the
medical needs such as ophthalmology.
year development program that formed part of
United States.
Philips ' continuous investment in healthcare R & D,
NEW SMALL MOLECULE FOR
totaling EUR 803 million in 2012.
GLAUCOMA TREATMENT: The Korea-based
76 THE MAZADA PHARMA GUIDE ●15 July- 21 July 2013