The mazda pharma Guide 15th Julu - 21st july 2013 | Page 75

�MACHINERY ARTICLE

BIO-POLYETHYLENE BOTTLES AS PRIMARY PACKAGING CONTAINER FOR AZILVA

SEMI-AUTOMATED, MODULAR LAB
Directive 2006 / 42 / EG.“ Our customers could
the risk of sample loss when using rapid protocols.
DEVICES— NEW FHM 1000 SERIES:
Bosch
already get a first impression of our development at
A new polypropylene material provides high
Packaging, one of the leading providers of process
the Crailsheimer Pharmatag. Their reactions have
transparency and minimizes leaching for safe and
and packaging technology, has introduced new
encouraged us to work even faster on the
reproducible assay data. Introduction of 5.0 mL
FHM 1000 series, a semi-automated, modular
development of the laboratory device,” Brenner
tubes will lead to 60 per cent reduction in plastic
laboratory devices for liquid pharmaceutical filling
said.
waste.
operations. FHM 1000 series is suitable for
DEBIOPHARM ' S BIOMARKER PROJECTS:
Eppendorf Vis Cuvettes are disposable
pharmacists and for the application in laboratories
Debiopharm Group, a Swiss-based global
cuvettes made of clear plastic with a light
and early clinical trials. Its filling parameters can be
biopharmaceutical group of companies, have signed
transmission of 300 nm to 900 nm. The visible
easily scaled-up to production systems: all relevant
a one-year collaboration agreement with Quartz Bio,
cuvettes are perfect tool for applications outside the
parameters are measured and specified in the
the clinical bioinformatics research organisation
UV range, for example, colorimetric protein assays
laboratory, and can then be transferred to production
leader in precision biomarker discovery.
( Bradford, Lowry, etc.), determining optical density
machines without further settings.
Under the research framework, Quartz Bio
of bacterial cultures( OD600 methods) and kinetic
The development of the FHM 1000
will apply its leading expertise in bioinformatics to
and flourescence measurements.
prototype was based on early involvement of
support Debiopharm translational projects in terms
Eppendorf ' s product range includes pipettes
customers and end users in the process.“ Our goal is
of computational analyses and biomarker discovery.
and automated pipetting systems, dispensers,
to offer our customers compact and modular
Projects are expected to range from preclinical nextamplification
centrifuges, mixers, spectrometers, and DNA
laboratory filling systems that support their
generation sequencing to clinical biomarker data
equipment as well as ultra-low
everyday working processes,” said Joachim
analyses.
temperature freezers, fermentors, bioreactors, CO2
Brenner, site manager Crailsheim and responsible
“ We are delighted to collaborate with
incubators, shakers, and cell manipulation systems.
for the pharma liquid product portfolio worldwide.
Debiopharm,” said Dr Jerome Wojcik, CEO of
Associated consumables like pipette tips, test tubes,
The FHM series significantly facilitates the design
Quartz Bio.“ Debiopharm ' s pioneering biomarker
microtiter plates, and disposable bioreactors
of experiments( DoE) for customers. Recording
projects are a unique opportunity for Quartz Bio to
complement the instruments for highest quality
parameters makes it possible to precisely determine
contribute to the implementation of Precision
workflow solutions.
cause-effect relationships between influencing
Medicine, thus demonstrating that bioinformatics
MVP PROGRAMME-- MENTOR LINE OF
factors and target variables by involving customers '
science can bring substantial benefits to patients.”
BREAST IMPLANT PRODUCTS: Valeant
experience.
“ We look forward to collaborating with
Pharmaceuticals International, Inc ' s Medicis
This“ user experience” approach has already
Quartz Bio,” commented Dr Hiroaki Tanaka,
division, a leader in facial injectables and
been successfully implemented within the Bosch
director of Personalized Medicine at Debiopharm.
professional skin care, has formed a collaboration
Group. In the electromobility sector, for instance,
“ Their longstanding clinical bioinformatics
with Mentor Worldwide LLC, the US market leader
the very early involvement of potential customers in
experience made them an ideal partner to support
in breast aesthetics, to enter certain of their nonthe
design and development process lead to a quick
our biomarker projects in our clinical trials and
reimbursed products into a combined physician
marketability of several products.“ Our new
extract from data the relevant information required
loyalty programme.
development was a good occasion to transfer this
for personalized therapy development.”
The new programme, called the M2VP
internal know-how to the pharmaceutical area. An
Quartz Bio SA is specialized in exploratory
( Medicis-Mentor Valued Partner) programme,
interdisciplinary team of development and market
biomarker data analyses for the generation of
extends the offerings of Medicis ' recently-launched
experts successfully implemented the user
precision medicine hypotheses.
MVP programme to include the MENTOR line of
experience approach for our new laboratory device
Debiopharm Group is focussed on the
breast implant products for a five-year term and is
FHM 1000,” said Andreas Groß, product manager at
development of prescription drugs that target unmet
for the US, subject to any geographical expansion
Bosch Packaging Technology.
medical needs. The group in-licenses and develops
that may be agreed upon by the parties.
The laboratory device series currently
promising biological and small molecule drug
The M2VP programme offers numerous incentives
consists of four different modules: the Human
candidates having reached clinical development
that reward utilization of various products across the
Machine Interface( HMI), the filling module, the
phases I, II or III, as well as earlier stage candidates.
Mentor and Medicis portfolios. Unlike other
weighing module and the needle movement. All
5.0 ML TUBES, CUVETTES: Eppendorf, a
programs in the space, the M2VP programme allows
automatic processes are operated from the HMI,
leading life science company that develops and sells
participating members to not only earn points that
which is the centerpiece of the laboratory device
instruments, consumables, and services for liquid-,
establish status within the programme, but to
FHM 1000. The filling process with its filling
sample-, and cell-handling in laboratories
redeem them for items such as product purchases. In
needle movement and in-process control( IPC)
worldwide, has launched 5.0 mL centrifuge tubes as
designing the programme, Mentor and Medicis
weighing are parameterized via the HMI, whereas
well as plastic cuvettes for measurements in visible
sought to address many of the issues that customers
in- and output of the packaging is done manually.
range.
felt existed with other programmes.
“ The recorded results and parameters can be scaled-
When working with samples between 2 and
" This will be an extremely valuable
up and transferred, for example to high-performance
5 mL, researchers often have no choice but to use
programme for me," said Dr. Tracy Hankins, a board
lines,” Groß explained.
tubes that are really designed for larger volumes,
certified plastic surgeon in Nevada, " I have utilized
The prototype operates with a peristaltic
typically 15 mL conical screw cap tubes. The new
products from both companies for years and now I
pump. Further filling modules are planned, for
Eppendorf tube 5.0 mL now provides the ' missing
can earn valuable rebates and rewards in one easy to
instance with a rotary slide piston pump. According
link ' for such samples, delivering a high-quality
understand loyalty programme."
to demand, the different filling systems can then be
solution for volumes up to 5 mL. These new tubes
" With this programme we are providing our
flexiblly exchanged. The integration of a closing
feature a practical and convenient snap cap for
customers with opportunities for volume-based cost
module is also planned, enabling packaging to be
single-hand operation and a compact conical design,
savings on the products they use and added
equipped with different types of stoppers. A
removing the contamination risks associated with
incentives to try other products from our combined
protective housing for both the filling module and
manipulating small volumes in large tubes.
portfolios," said Ryan Weldon, president of Medicis.
the needle movement ensure product and operator
Eppendorf tubes 5.0 mL are designed for safe and
" We believe that the M2VP programme is one of the
safety. All modules conform to the EU Machinery
stable centrifugation up to 25.000 x g, eliminating
most comprehensive loyalty programmes in the
THE MAZADA PHARMA GUIDE ●15 July- 21 July 2013 75