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Cite this article as: Beshish AG, Shamah R, Qian J, Keane-Lerner K, Morales PR, Zinyandu T, Davis J, Rosenblum JM & Viamonte HK. Is hyperoxia during veno-arterial extracorporeal life support due to cardiopulmonary failure associated with mortality in pediatric patients?. J Extra Corpor Technol 2025, 57, 129 – 136. https:// doi. org / 10.1051 / ject / 2025006.