A. G. Beshish et al.: J Extra Corpor Technol 2025, 57, 129 – 136 135
increased mortality using a derived cut-point within our cohort. Our secondary aim was to determine if hyperoxia during VA-ECLS is associated with greater odds of morbidity using the Functional Status Scale( FSS), and the development of complications while on ECLS, including acute kidney injury( AKI). The study protocol conformed to the Declaration of Helsinki and was approved by the institution’ s ethics committee in Children’ s Healthcare of Atlanta, Atlanta, Georgia, USA. Medical research is subject to ethical standards that promote and ensure respect for all human subjects and protect their health and rights.
This study was approved by the Children’ s Healthcare of Atlanta Institutional Review Board: Study ID No.( IRB # 00001239), approved on 10 / 11 / 2022.
Supplementary material
The supplementary material is available at https:// ject. edpsciences. org / 10.1051 / ject / 2025006 / olm.
Supplemental Table 1. Cardiac Diagnosis of Patient in the VA-ECLS Cohort.
Supplemental Table 2. Patient Demographics and Clinical Characteristics of Patients Who Required VA-ECLS Post-Cardiotomy Stratified by Mean PaO 2 Levels in the First 48 h into Non-Hyperoxia Group( PaO 2 233 mmHg), Hyperoxia Group( PaO 2 > 233mmHg).
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