Variables |
Non-hyperoxia group |
Hyperoxia group |
p-value |
Average PaO 2 £ 182 |
Average PaO 2 > 182 |
||
( n = 31 ) |
( n = 34 ) |
||
Age ( days ) |
6.0 [ 4.0 , 7.5 ] |
6.0 ( 4.3 , 7.0 ) |
0.984 |
Weight ( Kg ) |
3.1 [ 2.6 , 3.5 ] |
3.3 ( 2.8 , 3.6 ) |
0.641 |
Sex Male |
16 ( 52 %) |
24 ( 71 %) |
0.188 |
Female |
15 ( 48 %) |
10 ( 29 %) |
|
Race |
0.967 |
||
Caucasian |
15 ( 48 %) |
16 ( 47 %) |
|
African American |
14 ( 45 %) |
15 ( 44 %) |
|
Hispanic |
1 ( 3 %) |
2 ( 6 %) |
|
Other |
1 ( 3 %) |
1 ( 3 %) |
|
Gestational Age ( weeks ) |
38.0 [ 37.0 , 39.0 ] |
38.5 ( 37.0 , 39.0 ) |
0.323 |
Chromosomal Abnormality and Genetic Syndrome |
9 ( 29 %) |
5 ( 15 %) |
1 |
Primary Cardiac Diagnosis |
0.226 |
||
AA & critical AS |
2 ( 7 %) |
1 ( 3 %) |
|
DILV |
3 ( 10 %) |
1 ( 3 %) |
|
DORV |
1 ( 3 %) |
0 ( 0 %) |
|
HLHS |
22 ( 71 %) |
28 ( 82 %) |
|
Single Ventricle Other |
0 ( 0 %) |
3 ( 9 %) |
|
Tricuspid Atresia |
3 ( 10 %) |
1 ( 3 %) |
|
HLHS Variant |
0.2 |
||
MA / AA |
11 ( 50 %) |
15 ( 52 %) |
|
MA / AS |
1 ( 5 %) |
2 ( 7 %) |
|
MS / AA |
4 ( 18 %) |
10 ( 35 %) |
|
MS / AS |
6 ( 27 %) |
2 ( 7 %) |
|
Pre-Norwood Respiratory Support |
0.327 |
||
RA |
8 ( 26 %) |
10 ( 29 %) |
|
NC |
4 ( 13 %) |
10 ( 29 %) |
|
HFNC |
6 ( 19 %) |
4 ( 12 %) |
|
Intubated |
13 ( 42 %) |
10 ( 29 %) |
|
Pre-Norwood PGE1 Dose ( mcg / kg / min ) |
0.02 [ 0.01 , 0.02 ] |
0.02 ( 0.01 , 0.03 ) |
0.39 |
Preoperative VIS score |
0.0 [ 0.0 , 4.3 ] |
1.5 ( 0.0 , 7.8 ) |
0.155 |
Pre-Norwood Transthoracic Echocardiogram Atrioventricular Valve Regurgitation ( AVVR ) |
0.226 |
||
Moderate – Severe |
28 ( 90 %) |
25 ( 76 %) |
|
No – Trivial – Mild AVVR |
3 ( 10 %) |
8 ( 24 %) |
|
Systemic Ventricular Function |
0.713 |
||
Normal |
17 ( 55 %) |
18 ( 55 %) |
|
Mild Dysfunction |
2 ( 7 %) |
4 ( 12 %) |
|
Moderate – Severe Dysfunction |
12 ( 39 %) |
11 ( 33 %) |
|
Pre-Norwood Ascending Aorta Diameter ( mm ) Diameter ( mm ) |
3.30 [ 1.90 , 4.80 ] |
2.30 ( 1.90 , 3.70 ) |
0.148 |
Median z-score |
�3.10 [ � 4.44 , �2.55 ] |
�4.18 ( �4.57 , �3.30 ) |
0.16 |
Pre-Norwood ascending aorta groups based on diameter |
0.346 |
||
1.5 mm |
1 ( 3 %) |
2 ( 6 %) |
|
1.6 – 1.9 mm |
8 ( 26 %) |
8 ( 24 %) |
|
2.0 – 3.9 mm |
9 ( 29 %) |
16 ( 47 %) |
|
4.0 mm |
13 ( 42 %) |
8 ( 24 %) |
|
Source of pulmonary blood flow |
< 0.001 |
||
m-BTT shunt |
22 ( 71 %) |
6 ( 18 %) |
|
Sano Shunt |
9 ( 29 %) |
28 ( 82 %) |
|
Type of systemic ventricle |
0.235 |
||
LV |
8 ( 26 %) |
4 ( 12 %) |
|
RV |
23 ( 74 %) |
29 ( 85 %) |
|
Undetermined |
0 ( 0 %) |
1 ( 3 %) |
|
Intraoperative transesophageal echocardiogram Atrioventricular Valve Regurgitation ( AVVR ) |
0.881 |
||
Moderate – severe |
20 ( 77 %) |
20 ( 71 %) |
|
( Continued on next page ) | |||