Overall |
Year |
p-value |
Missing |
|||||
2019 |
2020 |
2021 |
2022 |
|||||
Number of cases |
40,777 |
10,261 |
9295 |
9731 |
11,490 |
|||
Use of cardioplegia |
< 0.001 |
0.1 |
||||||
Yes , cardioplegia |
39,211 ( 96.3 ) |
9832 ( 95.9 ) |
8901 ( 95.8 ) |
9392 ( 96.7 ) |
11,086 ( 96.7 ) |
|||
Yes , ventricular fibrillation |
36 ( 0.1 ) |
10 ( 0.1 ) |
6 ( 0.1 ) |
4 ( 0.0 ) |
16 ( 0.1 ) |
|||
None |
1470 ( 3.6 ) |
409 ( 4.0 ) |
382 ( 4.1 ) |
319 ( 3.3 ) |
360 ( 3.1 ) |
|||
Cardioplegia regime |
< 0.001 |
4.2 |
||||||
Continuous |
5094 ( 13.0 ) |
1339 ( 13.7 ) |
1272 ( 14.3 ) |
1245 ( 13.3 ) |
1238 ( 11.2 ) |
|||
Intermittent |
32,745 ( 83.8 ) |
8454 ( 86.3 ) |
7615 ( 85.7 ) |
8051 ( 86.3 ) |
8625 ( 78.0 ) |
|||
Single dose |
1239 ( 3.2 ) |
0 ( 0.0 ) |
0 ( 0.0 ) |
38 ( 0.4 ) |
1201 ( 10.9 ) |
|||
Number of doses , median |
3.00 [ 2.00 , 6.00 ] |
3.00 [ 2.00 , 6.00 ] |
4.00 [ 2.00 , 6.00 ] |
3.00 [ 2.00 , 6.00 ] |
3.00 [ 2.00 , 6.00 ] |
< 0.001 |
8.1 |
|
Total cardioplegia volume ( mL ), median |
2100.0 [ 1250.0 , |
2150.0 [ 1250.0 , |
2288.5 [ 1279.5 , |
2100.0 [ 1200.0 , |
2000.0 [ 1227.0 , |
< 0.001 |
5.1 |
|
3400.0 ] |
3500.0 ] |
3750.0 ] |
3400.0 ] |
3100.0 ] |
||||
Cardioplegia category |
< 0.001 |
3.3 |
||||||
None |
395 ( 1.0 ) |
109 ( 1.1 ) |
93 ( 1.0 ) |
92 ( 1.0 ) |
101 ( 0.9 ) |
|||
1:1 |
1 ( 0.0 ) |
0 ( 0.0 ) |
1 ( 0.0 ) |
0 ( 0.0 ) |
0 ( 0.0 ) |
|||
2:1 |
4 ( 0.0 ) |
1 ( 0.0 ) |
1 ( 0.0 ) |
1 ( 0.0 ) |
1 ( 0.0 ) |
|||
4:1 |
6689 ( 17.0 ) |
1809 ( 18.3 ) |
1357 ( 15.2 ) |
1348 ( 14.3 ) |
2175 ( 19.5 ) |
|||
8:1 |
5592 ( 14.2 ) |
1572 ( 15.9 ) |
1431 ( 16.0 ) |
1324 ( 14.0 ) |
1265 ( 11.3 ) |
|||
Crystalloid |
123 ( 0.3 ) |
43 ( 0.4 ) |
50 ( 0.6 ) |
29 ( 0.3 ) |
1 ( 0.0 ) |
|||
Variable |
2148 ( 5.4 ) |
561 ( 5.7 ) |
516 ( 5.8 ) |
448 ( 4.7 ) |
623 ( 5.6 ) |
|||
Crystalloid ( custodial ) |
841 ( 2.1 ) |
337 ( 3.4 ) |
200 ( 2.2 ) |
113 ( 1.2 ) |
191 ( 1.7 ) |
|||
Microplegia |
7687 ( 19.5 ) |
1666 ( 16.9 ) |
2063 ( 23.0 ) |
2129 ( 22.5 ) |
1829 ( 16.4 ) |
|||
del Nido |
15,835 ( 40.1 ) |
3770 ( 38.2 ) |
3236 ( 36.1 ) |
3941 ( 41.7 ) |
4888 ( 43.8 ) |
|||
Other |
122 ( 0.3 ) |
9 ( 0.1 ) |
8 ( 0.1 ) |
23 ( 0.2 ) |
82 ( 0.7 ) |
|||
Induction routes |
< 0.001 |
5 |
||||||
Antegrade-aortic root |
35,281 ( 91.1 ) |
8617 ( 88.3 ) |
8019 ( 90.8 ) |
8520 ( 92.3 ) |
10,125 ( 92.8 ) |
|||
Antegrade-coronary ostium |
513 ( 1.3 ) |
123 ( 1.3 ) |
124 ( 1.4 ) |
138 ( 1.5 ) |
128 ( 1.2 ) |
|||
Retrograde |
2935 ( 7.6 ) |
1017 ( 10.4 ) |
691 ( 7.8 ) |
575 ( 6.2 ) |
652 ( 6.0 ) |
|||
Maintenance route Antegrade-aortic root |
18,684 ( 62.6 ) |
4783 ( 63.6 ) |
4210 ( 60.2 ) |
4298 ( 60.2 ) |
5393 ( 65.9 ) |
< 0.001 |
26.8 |
|
Antegrade-coronary ostium ( left , right , |
2347 ( 7.9 ) |
583 ( 7.7 ) |
527 ( 7.5 ) |
501 ( 7.0 ) |
736 ( 9.0 ) |
< 0.001 |
26.8 |
|
or both ) |
||||||||
Antegrade-bypass graft |
2936 ( 9.8 ) |
650 ( 8.6 ) |
720 ( 10.3 ) |
752 ( 10.5 ) |
814 ( 9.9 ) |
< 0.001 |
26.8 |
|
Retrograde |
15,631 ( 52.4 ) |
4055 ( 53.9 ) |
3838 ( 54.9 ) |
3869 ( 54.2 ) |
3869 ( 47.2 ) |
< 0.001 |
26.8 |
|
Terminal warm reperfusate |
< 0.001 |
4.4 |
||||||
No |
22,647 ( 58.1 ) |
5867 ( 60.1 ) |
4915 ( 55.5 ) |
5167 ( 55.5 ) |
6698 ( 60.5 ) |
|||
Yes , standard |
1203 ( 3.1 ) |
355 ( 3.6 ) |
357 ( 4.0 ) |
330 ( 3.5 ) |
161 ( 1.5 ) |
|||
Yes , Buckberg |
124 ( 0.3 ) |
15 ( 0.2 ) |
68 ( 0.8 ) |
27 ( 0.3 ) |
14 ( 0.1 ) |
|||
Yes , blood only |
10,312 ( 26.4 ) |
2406 ( 24.6 ) |
2503 ( 28.2 ) |
2729 ( 29.3 ) |
2674 ( 24.2 ) |
|||
Yes , combination |
4424 ( 11.3 ) |
1125 ( 11.5 ) |
1019 ( 11.5 ) |
1037 ( 11.1 ) |
1243 ( 11.2 ) |
|||
Yes , microplegia |
293 ( 0.8 ) |
0 ( 0.0 ) |
0 ( 0.0 ) |
13 ( 0.1 ) |
280 ( 2.5 ) |