The Journal of ExtraCorporeal Technology Issue 55-1 | Page 45

J . Blanco-Morillo et al .: J Extra Corpor Technol 2023 , 55 , 30 – 38 37

reduced the influence of biases , excluding all the patients requiring early reintervention due to active bleeding or cardiac tamponade may have attenuated the effect of HAR in all outcome variables .

To conclude , HAR seems to be a promising approach that could be included as a perfusion tool for ERACS programs , to promote the recovery of patients in terms of BPR , endothelial glycocalyx preservation , and embolic protection , without representing additional risks when applied under the specified methodology . However , future randomized and controlled studies are required to confirm our findings .

Conflict of interest The authors declare no conflict of interest .

Funding

This research did not receive any specific grant from the public , commercial , or not-for-profit funding agencies .

Data availability

Requestors wishing to access a de-identified minimal dataset for monitoring purposes of our published analyses , can apply to Juan Blanco-Morillo .

Ethics Ethical approval is not required .

Author contributions

Juan Blanco-Morillo drafted the manuscript . Diego Salmerón conducted a critical review of the manuscript , performed the statistical analyses , and participated in the analysis and in the drafting of the manuscript . José María Arribas contributed to data interpretation and the critical review of the manuscript , and was involved in the study design . Piero Farina and Luc Puis reviewed the manuscript , and made substantial contributions to its final content . Piero Farina is responsible for the artwork . Ángel Sornichero provided the data and was involved in the study design . Sergio Juan Cánovas reviewed athe manuscript , and made substantial contributions to its final content . All authors read and approved the final manuscript .

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