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C URCUMIN —T HE 21 ST C ENTURY C URE
Antony B, Kizhakedath et al. Clinical evaluation of a herbal product (Rhulief™) in the
management of knee osteoarthritis. Abstract 316. Osteoarthritis Cartilage. 2011; 19(S1):
S145-S146
Rao TS, Basu N et al. Anti-inflammatory activity of curcumin analogues. Indian J Med
Res. 1982 Apr;75:574–578.
Funk JL, Ovarzo JN et al. Turmeric extracts containing curcuminoids prevent experi-
mental rheumatoid arthritis. J Nat Prod. 2006 Mar;69(3):351–355.
Aggarwal BB, Sung B. Pharmacological basis for the role of curcumin in chronic diseases:
an age-old spice with modern targets. Trends Pharmacol Sci. 2009; 30:85–94.
Liacini A, Sylvester J et al. Induction of matrix metalloproteinase-13 gene expression by
TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in
articular chondrocytes. J. Exp Cell Res. 2003 Aug 1;288(1): 208–217.
Chapter 5
Fujiwara H, Hosokawa M et al. Curcumin inhibits glucose production in isolated mice
hepatcytes. Diabetes Res Clin Pract. 2008 May;80(2):185–91. Epub 2008 Jan 24.
Weisberg SP, Leibel R et al. Dietary Curcumin Significantly Improves Obesity-Associated
Inflammation and Diabetes in Mouse Models of Diabesity. Endocrinology. 2008
Jul;149(7):3549–58. Epub 2008 Apr 10.
Kulkarni SK, Chopra K. Curcumin the active principle of turmeric (Curcuma longa), ame-
liorates diabetic nephropathy in rats. Clin Exp Pharmacol Physiol. 2006 Oct;33(10):
940–945.
Chapter 6
Depression
Sanmukhani J, Anovadiya A et al. Evaluation of antidepressant like activity of curcumin
and its combination with fluoxetine and imipramine: an acute and chronic study. Acta Pol
Pharm. 2011 Sep-Oct;68(5):769–75.
Garcia-Alloza M, Borrelli LA et al. Curcumin labels amyloid pathology in vivo, disrupts
existing plaques, and partially restores distorted neurites in an Alzheimer mouse model,
J. Neurochem. 102 (2007) 1095–1104.
Baker CB. Quantitative Analysis of Sponsorship Bias in Economic Studies of Antidepres-
sants. The British Journal of Psychiatry. 2003, 183: 498–506.
Kulkarni S, Dhir A et al. Potentials of curcumin as an antidepressant. ScientificWorld-
Journal. 2009 Nov 1;9:1233–41.
Kulkarni S, Bhutani MK et al. Antidepressant activity of curcumin: involvement of sero-
tonin and dopamine system. Psychopharmacology (Berl). 2008 Dec;201(3): 435–42. Epub
2008 Sep 3.
Dementia
Baum L et al. Six-month randomized placebo-controlled, double-blind, pilot clinical trial
of curcumin in patients with Alzheimer’s Disease. Journal of Clinical Psychopharmacolo-
gy. Vol 28, Number 1, Feb 2008 pg 110–114