CONTRACT RESEARCH & TOXICOLOGY a
Figure 5- Images at different time points of a volunteer treated with the active ingredient before & after BTA injection( a) & variation(%) in mean wrinkle length parameter with time for the different treatments vs. 14 days
Note: *** p < 0.001 vs. initial time at 4 months. Wilcoxon or Student’ s T-test used after checking the normality distributions by a Shapiro-Wilk test
Quantitative clinical data confirm that the combined regimen significantly delays the reappearance of wrinkles and improves skin surface parameters such as roughness and wrinkle length. These effects were sustained up to four months postinjection, exceeding the typical duration of BTA monotherapy.
For formulators and product developers in the speciality chemicals sector, these new findings underscore the value of multifunctional peptides in expanding the performance envelope of established dermatological treatments. Argireline Amplified peptide represents a compelling innovation
References: 1: Mintel, Attitudes Towards Cosmetic Procedures – UK, 2024. 2: B. K. Satriyasa, Clin. Cosmet. Investig. Dermatol., 2019, 12, 223 – 228. 3: C. M. Cheng, Clin. Interv. Aging, 2007, 2( 1), 81 – 83. 4: C. Blanes-Mira, J. Clemente, G. Jodas, A. Gill, G. Fernández-Ballester, B. Ponsati et al., Int. J. Cosmet. Sci., October 2002, 24( 5), 303 – 310. 5: C. Blanes-Mira, J. M. Merino, E. Valera, G. Fernández-Ballester, L. Gutiérrez, S. Viniegra et al., Neurochem., January 2004, 88( 1), 124 – 135. 6: R. Mestre, N. García, T. Patiño, M. Guix, J. Fuentes, M. Valerio-Santiago et al., Biofabrication, August 2021, 13( 4). in the dermatological space, aligning with market demand for synergistic, non-invasive anti-ageing solutions that deliver measurable, durable outcomes. ●
*- Also contributing to this article were Belén Aguirre and Raquel Delgado
**- Argireline is a registered trademark of The Lubrizol Corporation or its affiliates
Bianca McCarthy
GLOBAL STRATEGIC MARKETING MANAGER
LUBRIZOL k + 81 80 2263 8643 J bianca. mccarthy @ lubrizol. com j https:// www. lubrizol. com /
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