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Advancing Non-Invasive Cancer Diagnostics with Extracellular Vesicles
My team focuses on extracellular vesicles( EVs) as biomarkers for early cancer detection. All cell types secrete EVs containing proteins, lipids and nucleic acids that reflect their origins. These nanovesicles offer valuable insights into health and disease, including cancer.
Dr Lee Wai Leng
lee. wai. leng @ monash. edu
Senior Lecturer
Expertise
Expertise Proteomics for disease marker Public discovery health Education
Extracellular vesicles as Financial markers for statistics human disease
Non-invasive disease detection
I worked with spectroscopic experts from Monash University Australia, oncologists from University of Malaya and industry partners, to develop a non-invasive urine
test for prostate cancer, which won the silver medal at ITEX 2020. We are currently collaborating with Selayang Hospital, Universiti Kebangsaan Malaysia Hospital, and Sunway Medical Center to further improve the detection model.
EVs carry biomolecules for cancer diagnosis
I am also integrating artificial intelligence into this field through collaborations with AI engineers. Together, we developed an AI-based model that analyzes urinary EV spectral data to enhance cancer prediction accuracy.
Our regional research network has gained international recognition, contributing to the Horizon Europe project“ VOLATEVS,” which explores volatile organic compounds emitted by EVs as a new avenue for disease diagnosis.
My research focuses on leveraging extracellular vesicles and AI to develop non-invasive cancer detection approaches and bridges molecular biology, biospectroscopy and clinical collaborations to drive innovation in early disease detection
SCHOOL OF SCIENCE CAPABILITIES