ReMed 2017 ReMed Magazine N°3 - Lifestyle | Page 9

ReMed Magazine | Sciences de la santé ReMed Magazine Sciences de la Santé The AREDS formulation is not a cure. It does not help people with early AMD, and will not restore vision already lost from AMD. But it may delay the onset of late AMD. It may also help slow vision loss in people who already have late AMD. Advanced neovascular AMD: neovascular AMD typically results in severe vision loss. Different therapies such as intravitreal anti-VEGF injections, dynamic photothera- py and laser procedures are used to stop further vision loss and, in some cases, visual acuity was improved in a significant number of cases. Conclusion Multiple recent studies, particularly AREDS, allowed better understanding of possible links between diet and lifestyle factors that potentially influence the onset of AMD, thus allowing better prevention. (An ounce of prevention is worth a pound of cure)-B.F References {1} (Lee P.P., Feldman Z.W., Ostermann J., Brown D.S., Sloan F.A. Longitudinal prevalence of major eye diseases Arch Ophthalmol 2003 ; 121 : 1303-1310) {2} (Mitchell P., Wang J.J., Smith W., Leeder S.R. Smoking and the 5-year incidence of age-related maculopathy: the Blue Mountains Eye Study Arch Ophthalmol 2002 ; 120 : 1357-1363) (Chakravarthy U., Augood C., Bentham G.C., de Jong P.T., Rahu M., Seland J., and al. Cigarette smoking and age-related macular degeneration in the EUREYE Study Ophthalmology 2007 ; 114 : 1157-1163) {3} (Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in etiology of Age-Related Macular Degeneration Stephen Burgess, George Davey Smith, MD, DSc Manuscript no. 2016-1021.) {4} (Klein R., Deng Y., Klein B.E., Hyman L., Seddon J., Frank R.N., and al. Cardiovascular disease, its risk factors and treat- ment, and age-related macular degeneration: Women’s Health Initiative Sight Exam ancillary study Am J Ophthalmol 2007 ; 143 : 473-483. {5} (Clemons TE, Kurinij N, Sperduto RD; AREDS Research Group. Associations of mortality with ocular disorders and an intervention of high-dose antioxidants and zinc in the Age-Related Eye Disease Study: AREDS Report No. 13. Arch Ophthalmol 2004; 122:716–26.) {6} (Seddon J.M., Cote J., Davis N., Rosner B. Progression of age related macular degeneration: association with body mass index, waist circumference, and waist-hip ratio Arch Ophthalmol 2003 ; 121 : 785-792) {7} (Delcourt C., Carrière I., Ponton-Sanchez A., Fourrey S., Lacroux A., Papoz L., and al. Light exposure and the risk of age-related macular degeneration: les Pathologies Oculaires Liées à l’Age (POLA) study Arch Ophthalmol 2001; 119: 1463-1468) {8} (Flood V., Smith W., Wang J.J., Manzi F., Webb K., Mitchell P. Dietary antioxidant intake and incidence of early age-re- lated maculopathy: the Blue Mountains Eye Study Ophthalmology 2002 ; 109 : 2272-2278) {9} (Age-Related Eye Disease Study Research Group, SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol 2007; 125:1225–32) {10} (SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, Lindblad AS, et al. The relationship of dietary ca- rotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol 2007; 125:1225–32.) {11} (Chong E.W., Kreis A.J., Wong T.Y., Simpson J.A., Guymer R.H. Dietary omega-3 fatty acid and fish intake in the pri- mary prevention of age-related macular degeneration: a systematic review and meta-analysis Arch Ophthalmol 2008 ; 126 : 826-833) {12} (Age-Related Eye Disease Study Research Group, SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol 2007; 125:1225–32.) {13} (Van Leeuwen R., Boekhoorn S., Vingerling J.R., Witteman J.C., Klaver C.C., Hofman A., and al. Dietary intake of antioxidants and risk of age-related macular degeneration JAMA 2005 ; 294 : 3101-3107) {14} (Tan J.S., Wang J.J., Flood V., Rochtchina E., Smith W., Mitchell P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study Ophthalmology 2008 ; 115 : 334-341) (Delcourt C., Cristol J.P., Tessier F., Léger C.L., Descomps B., Papoz L.Age-related macular degeneration and antioxidant status in the POLA study. POLA Study Group Pathologies Oculaires Liées à l’Age Arch Ophthalmol 1999; 117: 1384-1390) {15} (AALC) ASSOCIATION ALGERIENNE DE LUTTE CONTRE LA CECITE ReMed 2017 | Numéro 2 | Numéro 3 ReMed 5 9