Unfortunately, you find these interfering prying people as so-called friends and family members who say they love you ... they care about you; always wishing you well. Even some who say they will keep you in prayer. Wow!! ,It's bad enough that strangers, even enemies or just colleagues seek your downfall. You expect that from them because they don't love you and they don't care about you and definitely do not hide it. But when those whom "supposedly" love you or "supposedly are" close; it's a CRYING shame. Yes, they make you want to run away and cry! They come to you pretending it's in your best interest or someone else's. When in fact it's in their best interest. Think about it ... who loses? So, at the end of the day and when the meddling has tainted your life ... who stays dealing with the results and who walks away to continue doing what they do best ...hmmm... (just saying).
Personally, I don't have time for other people's business and wish others were busy enough to stay out of mine and others. So how do you deal with them? Should you be polite or as heartless as they are .... hmmmm????
You could respond from a psychological point of view and just say ... "you are showing an interest in my life so you will feel good about yours." It may shock them to hear this but 99.9% of the time it is so true.
On the other hand, if you don't know the nosey person well, then just ignore them. After all you should feel sorry for them, because they are looking day and night for any clue or opening in other people's lives that will make them feel good about their own.