CLINICOPATHOLOGIC REVIEW:
Papillary Lesions of the Oral Cavity
Authors
Clinical History
Tessie Buraczewski DMD
A 52-year-old African American female presented to the University of Pittsburgh School
of Dental Medicine with a chief complaint of “a toothache.” During her head and neck
examination, an asymptomatic, 1.0 x 0.5 cm, exophytic, pink-white, pedunculated lesion
with surface finger-like projections was noted on the right anterior buccal mucosa near
the commissure. (Figure 1) The lesion had been present for approximately five years and
was reported to be slowly enlarging. Her medical history was significant for hypertension,
angina, cardiac arrhythmia with catheterization, heart murmur, bipolar disorder, depression,
and unspecified gastroesophageal problems, as well as asthma and emphysema. Her
medications included an antihypertensive (lisinopril), an antilipemic agent (Zocor®),
an antipsychotic drug (Compazine®), an antidepressant (Emsam®), and albuterol for the
treatment of asthma and emphysema. Her social history was significant for past illicit
drug use, from which she had recently recovered. The patient was lost to follow-up and,
to the best of our knowledge, an excisional biopsy was never performed.
Resident, Oral and Maxillofacial
Pathology, University of Pittsburgh
Medical Center
tmb55@pitt.edu
Joanne L. Prasad DDS
Assistant Professor, Department of Oral
Biology and Department of Diagnostic
Sciences, School of Dental Medicine,
University of Pittsburgh
Address:
G-132, 3501 Terrace Street,
Pittsburgh, PA 15261
Figure 1.
A clinical photograph depicting a raised,
pedunculated mass of the right commissure
area with surface finger-like projections.
Given the information
provided, what is the
most likely diagnosis?
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N O V / D E C 2 0 1 6 | P E N N S Y LVA N I A D E N TA L J O U R N A L
A.
B.
C.
D.
E.
Squamous papilloma
Verruca vulgaris
Condyloma acuminatum
Verruciform xanthoma
Sialademoma papilliferum