Migraine Report Migraine-Report | Page 5

Project Progress Report  Patient with abnormal renal function or abnormal liver function, evidence of cirrhosis or portal hypertension  Patient with known history of HIV 1 and HIV 2, Hepatitis B or C infection or syphilis infection  Patient suffering from malignancy, mental illness or any other cardio vascular disease 3. Concomitant Medications  Patients on steroids 4. Allergy/Intolerance  Patients with known history of hypersensitivity to any medication 5. Substance Abuse  Patients consuming alcohol > more than 2 ounce a day 6. Participation in clinical trial previously  Patient must not have used another investigational agent/device or participated in a clinical trial within the last 30 days prior to enrollment. 7. Others  Pregnant or lactating woman  Women of childbearing potential not practicing contraception Randomized controlled clinical trial to evaluate prophylactic 5 properties of Ayu rv ed ic Treatment Protocol in refractory and chronic migraine patients