LMS Volume 33 |ssue 4 | Página 39

Rapid Testing Rapid Quantum Detection T o monitor product quality effectively, it is critical to test for microbial contamination throughout the manufacturing process. However, traditional microbiological methods require several days to obtain test results. In order to keep pace with today’s increasing production demands, one needs to reduce the time to result to be able to address contamination events sooner, avoid line shutdowns, release product to the market faster and reduce warehousing costs. It also enables one to improve control and understanding of the manufacturing process. Merck Millipore offers the solution with the Milliflex® Quantum system. It is a rapid fluorescent-based technology designed for the fast quantitative detection of microorganisms over a broad range of filterable matrices. This easy-to-use system uses industry standard membrane filtration techniques to detect viable and culturable microorganisms down to 1CFU per sample. The nondestructiveness­of this method also allows one to identify any microorganisms detected during the initial fluorescent count, using current ID methodology. This system can be used for raw material (media, buffers and water), in-process samples (bioburden prior to sterilisation, CIP/SIP samples and cell culture/fermentation samples) final products and environmental samples. The Milliflex features: • Non-destructive method that enables reliable identification using any ID technology • Easy-to-use system that requires minimal training • Results comparable to compendia method, enabling faster validation • Compact hardware that fits on any laboratory bench. By combining the Milliflex® products, accessories and services, one can immediately streamline their microbial contamination testing workflow, leverage their quality assurance level by avoiding risks of exogenous contamination and ensure compliance to all GMP/GLP requirements. ⚛ Merck Millipore Field Marketing Manager: Melanie May Tel: 011-372-5027 Email: melanie.may@merckgroup.com LMS  Issue 4 | 2014  39