Journal of Rehabilitation Medicine 51-8 | Page 57

Psychometric measurement of PEI in chronic musculoskeletal pain Table VII. Patient Enablement Instrument (PEI) median and interquartile range (IQR) scores of participants with chronic pain based on their answers on the Global Perceived Effect (GPE) (anchor) Patient Enablement Instrument All participants Global perceived effect WAD CR MixCP n  =  516 (%) Median (IQR) n  =  116 (%) Median (IQR) n  =  115 (%) Median (IQR) Very much improved/ Completely recovered 14 (2.7) Much improved 105 (20.3) Improved 200 (38.8) Unchanged 154 (29.8) Worsened 31 (6.0) Much worsened 10 (1.9) Very much worsened 2 (0.4) 11 (9–12) 7 (6–9) 4 (2–6) 1 (0–3) 0 (0–2) 0 (0–2) 1 (0–1) 1 (0.9) 21 (18.1) 55 (47.4) 31 (26.7) 8 (6.9) 0 (0.0) 11 (11–11) 8 (6–11) 5 (3–6) 2 (1–3) 0 (0–1) 9 (7.8) 51 (44.3) 44 (38.3) 4 (3.5) 4 (3.5) 3 (2.6) n  =  285 (%) Median (IQR) 12 (9–12) 7 (6–10) 4 (2–6) 0 (0–2) 0 (0–1) 0 (0–0) 4 (1.4) 33 (11.6) 101 (35.4) 119 (41.8) 19 (6.7) 7 (2.5) 2 (0.7) 9 6 4 1 1 1 1 (9–10) (6–7) (2–6) (0–3) (0–3) (0–3) (0–1) IQR: interquartile range; WAD: whiplash-associated disorders; CR: cervical radiculopathy; MixCP: mixed chronic pain. CSQ catastrophizing after treatment was moderate (r Sp  = 0.552). All other correlations between PEI and self-reported measures were fair (r Sp  = –0.250–0.380), except for none to little correlations between PEI score and the change between baseline and after treatment in the EQ-5D Index and self-reported work ability. In all groups the correlations between PEI score and socio- demographic variables at baseline were none to little. Self-rated change 593 All the 516 participants included in the factor ana- lysis had complete data for the PEI and GPE scores. The correlation between the PEI and GPE was good (r Sp  = –0.69, p < 0.001, Table VII). Ten participants re- ported a large deterioration and 2 participants a very large deterioration; they were excluded from further analyses, since this number was too small to determine the SRC for deterioration (29). For the WAD, CR and MixCP groups the correlations between the PEI and GPE were r Sp  = –0.72, –0.70 and –0.60, respectively. The SRC ROC , defined as the most optimal ROC cut-off point, was found at a PEI score of 5 points for all participants, and had a sensitivity of 85% and a specificity of 82% (see Figs 1a–d). These findings correspond to a misclassification of 33% of the parti- cipants. The positive predictive value (PPV) was 59% and the negative predictive value (NPV) was 95%. The overall model quality was 0.87. For the WAD group, the SRC ROC was found at a PEI score of 5 points and had a sensitivity of 96% and a specificity of 75%, corresponding to a misclassification of 30% of the participants. The PPV was 47% and the NPV was 99%. The overall model quality was 0.86. For the CR group, the SRC ROC was found at a PEI score of 6 points and had a sensitivity of 85% and a specificity of 69%. These findings correspond to a misclassification of 43% of the participants. The PPV was 76% and the NPV was 80%. The overall model quality was 0.79. For the MixCP group, the SRC ROC was found at a PEI score of 4 points and had a sensitivity of 89% and a specificity of 77%, corresponding to a misclassification of 32% of the participants. The PPV was 40% and the NPV was 98%. The overall model quality was 0.86. DISCUSSION The results of this study suggest that the PEI demon- strates fair measurement properties (content validity, construct validity, and internal consistency) in parti- cipants with chronic musculoskeletal pain treated in different settings. Higher patient enablement scores were related to better health after treatment and to positive changes in health between baseline and after treatment. The PEI may be a valid outcome measure for use in the long-term management of participants with chronic musculoskeletal pain, although the instrument may need further development (see below). Content validity of the Patient Enablement Instrument Only a few patients did not complete the questionnaire, or found the PEI questions “not applicable”, suggesting that most patients considered the questions relevant to their condition. This contrasted with another Swedish study in which many patients (39%) consulting a ge- neral practitioner (GP) in primary care characterized at least 1 of the questions as not applicable (19). A large study performed in primary care in England (30) found that a larger percentage of patients with longstanding illnesses (53.6% vs 46.0%), or above-average consul- tation rates (31.1% vs 24.8%) completed the PEI. It is possible that patients who received an intervention over time find the PEI questions more relevant compa- red with those who completed the questionnaire after consultation with a GP. Construct validity of the Patient Enablement Instrument CFA showed the 1-factor PEI model had approximate fit to the data for all 4 groups, with all SRMR values < 0.08, and standardized residual correlations were J Rehabil Med 51, 2019