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Comprehensive assessment for hospital-acquired deconditioning in acute hospitals overall performance can be readily quantified, and expected population norms should also be developed. Any new HAD assessment instrument also requires extensive reliability testing. This was a critical omis- sion in 5 of the included instruments. Information on expected variability in performance of body systems is urgently required over a typical inpatient hospital stay, for different sex-age groups, so that abnormal deterioration of body systems can be readily identified (2, 4, 5, 7). The development of a new comprehensive HAD as- sessment instrument could be integrated with quality care and discharge planning standards, and hospital accreditation requirements (2–4, 14). It is counterin- tuitive, and makes no economic, social or functional sense to allow people to decondition whilst in hospital, and to leave hospital in poorer health than when they were admitted (1, 3–5). Regular application of a com- posite test battery will identify incipient HAD before it becomes an issue, and promote healthy ageing in, and out of, hospital. It could also underpin integrated inter-professional practice (14, 16). A comprehensive assessment instrument should be able to be delivered by any healthcare provider from any discipline (e.g. doctor, nurse, physiotherapist, occupational therapist, healthcare assistant). Because it uses a standard ap- proach, the findings could then be readily understood and discussed at inter-professional discharge planning meetings for HAD risk identification and mitigation strategies (6, 7, 9, 14). Not all the Creditor HAD items were addressed in the included assessment instruments (e.g. deminera- lization (markers for osteoporosis), nutritional status/ usual food intake, sensory “continence”, urinary con- tinence and polypharmacy) (12). Whilst items such as balance, function, mobility, skin integrity could readily be assessed and re-assessed over short time- periods, measures such as demineralization, nutrition, appetite, perceived health status, sensory deprivation (hearing, vision, touch, taste, smell, etc.), osteoporosis and polypharmacy are more appropriate to longer-term reflective measurement periods (2, 4, 10). These mea- sures lend themselves to comprehensive assessment on hospital admission, to detect already declining function and frailty (5). Moreover, proxy measures of demi- neralization could be inferred from anthropometric measures, mobility, balance and muscle strength, and sensory “continence” is integral to successful comple- tion of all physical tests (2, 4, 5). However, urinary (and faecal) continence can change over short time-periods, and thus its assessment should be included in any new HAD instrument (34). This systematic evidence scan identified that at least 12 tests of performance in different body systems are 403 required for comprehensive assessment for incipient HAD (see Tables II and III). Whilst condition-specific assessments were deliberately excluded in order to find general HAD assessments, the included assessment items could also be applied to people with known chronic conditions to ensure that they do not decondition whilst receiving care requiring bed rest. Study limitations The comprehensiveness of the search was potentially limited by the lack of agreed characteristics of HAD, against which assessment items from the identified instruments could be aligned. Moreover, the breadth of the evidence scan was potentially limited by incon- sistencies in nomenclature describing deconditioning, functional decline and frailty. The search may thus have failed to identify all relevant HAD assessment literature. The focus on general HAD assessment items (non-condition-specific) may have limited iden- tification of relevant items that had been developed for chronic conditions or disease, but were, in fact, transferable to global HAD assessment. Conclusion No single assessment instrument currently assesses HAD comprehensively. HAD should largely be identi- fiable with regular targeted, comprehensive assessment of performance of multiple body systems, in order to detect early changes. This would support preventative interventions during the hospital stay and restorative interventions on discharge. REFERENCES 1. Gillis A, MacDonald B. Deconditioning in the hospitalized elderly. Can Nurse 2005; 101: 16–20. 2. Falvey JR, Mangione KK, Stevens-Lapsley JE. Rethinking hospital-associated deconditioning: proposed paradigm shift. Phys Ther 2015; 95: 1307–1315. 3. Kleinpell RM, Fletcher K, Jennings BM. Chapter 11, Redu- cing functional decline in hospitalized elderly. 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