Journal of Rehabilitation Medicine 51-1CompleteIssue | 页面 69

66 G. Müller et al. Table VI. Mean direct and indirect medical costs per year by treatment group, in EUR Direct medical costs Total costs within two years pre intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention Direct back pain medical costs Total costs within two years pre intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention Indirect medical costs Total costs within two years pre intervention BE   ST BE–ST Mean (SD)   Mean (SD) Difference % 95% CI  –4 [–692; 437] p 3,215 (5,998) 3,343 (4,329) –128 2,173 (3,355) 2,446 (4,906) –272 –11 [–644; 99] 0.151 1,799 (3,554) 3,972 (6,155) 2,289 (6,322) 4,735 (9,783) –491 –763 –21 [–917; –64] –16 [–1,467; –59] 0.024 0.034 7 1 0.658 571 (1,686)   564 (1,424) [–156; 169] 0.935 242 (1,056)   471 (252) –228 –49 [–377; –80] 0.003 242 (1,233) 485 (1,709)     253 (1,839) 723 (3,248) –10 –239 –4 [–148; 127] –33 [–451; –27] 0.883 0.027 –5 [–666; 398] 0.620 2,711 (5,362)   2,845 (5,323) –134 2 nd year post intervention Total costs within two years post intervention 1,368 (3,634)   2,563 (7,767) –119 –47 [–1,673; –716] < 0.001 1,286 (3,718) 2,654 (5,637)   1,574 (4,009)   4,137 (9,032) –288 –148 –18 [–664; 87] 0.132 –36 [–2,129; –836] < 0.001 Indirect back pain medical costs Total costs within two years pre intervention 895 (276)   967 (3,798) 72 434 (2,303)   787 (4,721) –353 –45 [–650; –56] 0.020 378 (2,788) 812 (3,737)   365 (2,516)   1,152 (5,455) 13 –340 4 [–259; 284] –30 [–754; 73] 0.926 0.107 1 st year post intervention 1 st year post intervention 2 nd year post intervention Total costs within two years post intervention 7 [–371; 228] 0.639 SD: standard deviation; CI: confidence interval; BE: back exercise; ST: standard treatment. Table VII. Difference in direct medical costs (total costs within two years post intervention) of back exercise and standard treatment Cost areas Difference % 95% CI Drugs Therapeutics Outpatient Hospital Sick pay Rehabilitation Back exercise Total –207 –36 –66 –463 –431 –28 467 –763 –22 –16 –5 –36 –53 –29 97 –16 [–480; 66] 0.318 [–75; 3] 0.069 [–177; 57] 0.248 [–855; –71] 0.021 [–693; –169] 0.001 [–74; 18] 0.235 [443; 492] < 0.001 [–1,467; –59] 0.034 effects are realized simultaneously with cost savings. Exercising is cost-effective (p < 0.05) at a maximum willingness to pay of 4,370 EUR at grade 3 GCPS, 7,500 EUR at grade 2, and 19,300 EUR at grade 1 (Table XI). MWTP values for the individual GCPS grades were determined by iterations. p CI: confidence interval. Table VIII. Back pain and functional impairments during the last 6 months (pre intervention = t0, 1 st year post intervention = t2, 2 nd year post intervention = t4) BE   ST   BE-ST Mean (SD)   Mean (SD)   Difference 6.9 (2.0)   6.4 (2.4)   2 nd year post intervention 4.8 (2.4)   5.7 (2.6)   –0.9 –15.9 [–1.2; –0.6] < 0.001 4.5 (2.4)   5.5 (2.6)   –1.0 –17.8 [–1.3; –0.6] < 0.001 Mean back pain  Within six months pre 5.1 (2.0)   4.9 (2.3)   2 nd year post intervention 3.4 (2.0)   4.4 (2.4)   –1.0 –23.3 [–1.3; –0.8] < 0.001 3.2 (2.1)   4.1 (2.3)   –0.9 –21.8 [–1.2; –0.6] < 0.001 Impairment of daily activities  Within six months pre intervention 3.8 (2.3)   3.7 (2.6)   2.3 (2.2)   3.3 (2.6)   –1.0 –30.5 [–1.3; –0.7] < 0.001 2.2 (2.2)   3.0 (2.5)   –0.8 –27.1 [–1.1; –0.5] < 0.001 Severest back pain Within six months pre intervention 1 st year post intervention 1 st year post intervention 1 st year post intervention 2 nd year post intervention Days with pain Within six months pre intervention 0.1 0.1 95% CI 8.6 [0.3; 0.8] 2.7 [–0.10.3] 3.0 [–0.1; 0.3] < 0.001 0.197 0.358 86.7 (62.6)   87.6 (67.5)   –0.9 52.5 (60.7)   75.0 (67.3)   –22.5 –30.0 [–30.7; –14.3] < 0.001 2 nd year post intervention 48.9 (57.7)   68.3 (64.7)   –19.4 –28.4 [–27.5; –11.3] < 0.001 2.2 (1.0)   2.2 (1.1)   1.5 (0.9)   2.1 (1.2)   –0.5 –26.0 [–0.7; –0.4] < 0.001 1.5 (0.9)   1.9 (1.1)   –0.4 –20.0 [–0.5; –0.2] < 0.001 1 st year post intervention 2 nd year post intervention SD: standard deviation; BE: back exercise; ST: standard treatment. www.medicaljournals.se/jrm 0.0 –1.1 [–7.3; 5.4] p 1 st year post intervention Graded Chronic Pain Status  Within six months pre intervention 0.5 % 0.9 [–0.1; 0.1] 0.775 0.722