Journal of Rehabilitation Medicine 51-10 | Page 67
2013; 21: 493–496.
41. Olausson P, Gerdle B, Ghafouri N, Sjostrom D, Blixt E,
Ghafouri B. Protein alterations in women with chronic
widespread pain – an explorative proteomic study of the
trapezius muscle. Sci Rep 2015; 5: 11894.
42. Stensson N, Ghafouri B, Gerdle B, Ghafouri N. Alterations
of anti-inflammatory lipids in plasma from women with
chronic widespread pain – a case control study. Lipids
Health Dis 2017; 16: 112.
43. Khoonsari PE, Ossipova E, Lengqvist J, Svensson CI, Ko-
sek E, Kadetoff D, et al. The human CSF pain proteome.
J Proteomics 2019; 190: 67–76.
44. Kelleher JH, Tewari D, McMahon SB. Neurotrophic factors
and their inhibitors in chronic pain treatment. Neurobiol
Dis 2017; 97: 127–138.
45. Indo Y. Neurobiology of pain, interoception and emotional
response: lessons from nerve growth factor-dependent
neurons. Eur J Neurosci 2014; 39: 375–391.
46. Leite VF, Buehler AM, El Abd O, Benyamin RM, Pimentel
DC, Chen J, et al. Anti-nerve growth factor in the treat-
ment of low back pain and radiculopathy: a systematic
review and a meta-analysis. Pain Physician 2014; 17:
E45–E60.
47. Laske C, Stransky E, Eschweiler GW, Klein R, Wittorf A,
Leyhe T, et al. Increased BDNF serum concentration in
fibromyalgia with or without depression or antidepres-
sants. J Psychiatr Res 2007; 41: 600–605.
48. Grimsholm O, Rantapaa-Dahlqvist S, Dalen T, Forsgren S.
BDNF in RA: downregulated in plasma following anti-TNF
treatment but no correlation with inflammatory parame-
ters. Clin Rheumatol 2008; 27: 1289–1297.
787
49. Simao AP, Mendonca VA, de Oliveira Almeida TM, Santos
SA, Gomes WF, Coimbra CC, et al. Involvement of BDNF in
knee osteoarthritis: the relationship with inflammation and
clinical parameters. Rheumatol Int 2014; 34: 1153–1157.
50. Generaal E, Milaneschi Y, Jansen R, Elzinga BM, Dekker J,
Penninx BW. The brain-derived neurotrophic factor pat-
hway, life stress, and chronic multi-site musculoskeletal
pain. Mol Pain 2016; 12: pii: 1744806916646783.
51. Castren E, Kojima M. Brain-derived neurotrophic factor in
mood disorders and antidepressant treatments. Neurobiol
Dis 2017; 97: 119–126.
52. Giese M, Unternaehrer E, Brand S, Calabrese P, Holsboer-
Trachsler E, Eckert A. The interplay of stress and sleep
impacts BDNF level. PLoS One 2013; 8: e76050.
53. Giese M, Unternahrer E, Huttig H, Beck J, Brand S, Ca-
labrese P, et al. BDNF: an indicator of insomnia? Mol
Psychiatry 2014; 19: 151–152.
54. Gerdle B, Ernberg M, Mannerkorpi K, Larsson B, Kosek E,
Christidis N, et al. Increased interstitial concentrations of
glutamate and pyruvate in vastus lateralis of women with
fibromyalgia syndrome are normalized after an exercise
intervention – a case-control study. PLoS One 2016; 11:
e0162010.
55. Ernberg M, Christidis N, Ghafouri B, Bileviciute-Ljungar
I, Lofgren M, Larsson A, et al. Effects of 15 weeks of re-
sistance exercise on pro-inflammatory cytokine levels in
the vastus lateralis muscle of patients with fibromyalgia.
Arthritis Res Ther 2016; 18: 137.
56. Birklein F, Schmelz M, Schifter S, Weber M. The important
role of neuropeptides in complex regional pain syndrome.
Neurology 2001; 57: 2179–2184.
Effect of exercise on neurotrophin levels in patients with FM
J Rehabil Med 51, 2019