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One of the best known cases other than that of the cloning of the dolly
sheep is the insulin cows, and this deals with an Argentine
pharmaceutical company named Bio Sidus; Since 2007 has a group of
cattle that has modified a gene in its genome, which makes these cows
modified, produce milk with insulin, Insulin is a very expensive
medicine and with these cows its cost and the way of supply would be
continuous, helping the sector of the population suffering from
diabetes types one, two or even three. Patagonia calves were modified
DNA with the precursor gene of human insulin and not with insulin
protein because "it would be a risk that it would pass into the blood
because glucose levels would fall," said Dr. Andrés Bercovich, manager
of the draft. With 25 cows will be sufficient to cover the total demand of
human insulin of Argentina The precursor consists of a human insulin
molecule to which has been added a small fragment of protein that
changes its spatial structure and makes it inactive in the animal. The
precursor gene for human insulin is only active in the mammary glands
of cattle, since the goal is to obtain insulin from milk.
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