National Institutes of Health
Grant type : NIH Research Project Grant Program ( R01 )
Title : “ Metabolic Profiling and Comprehensive Metabolic Pathway Mapping : a Systems Biology Approach to Cardiovascular Failure and Organ Injury Following Infant Congenital Heart Disease Surgery ”
At the close of 2023 , Jesse A . Davidson , MD , was in his third year of a five-year grant awarded by the NIH in the amount of $ 3,144,430 . The Research Project Grant ( R01 ) is the oldest grant mechanism used by NIH and provides support for health-related research and development based on the mission of the NIH . A quarter of children with congenital heart disease undergo intervention in the first year of life , often requiring surgery with cardiopulmonary bypass . Mortality for high-risk surgeries remains greater than 10 % and major complications occur in 30 % of these complex surgeries . Dr . Davidson believes that novel diagnostic , mechanistic and therapeutic approaches are critically needed to reduce this burden on our infants , families and healthcare system . His study is a combined clinical cohort study and pre-clinical large animal study to determine the metabolic changes associated with cardiovascular failure and organ injury following infant cardiac surgery .
World Children ’ s Initiative
Grant type : Project K : Legacy Grant Title : “ Virtual Reality Applications for Patients with Congenital Heart Disease ” World Children ’ s Initiative ( WCI ) created The Project K : Legacy Grant , in honor of Kanishka Ratnayaka , MD , an internationally renowned pediatric interventional cardiologist that passed away in 2021 due to colon cancer . The grant seeks to recognize and promote the work of an individual who embodies Dr . Ratnakaya ’ s commitment to cutting-edge research with the potential to improve healthcare access for children . In September 2023 , WCI awarded the inaugural The Project K : Legacy Grant in the amount of $ 39,000 to Jenny E . Zablah , MD , at Children ’ s Colorado . VR has been used as a tool for medical education as a procedure can be repeated unlimited times ; through practice , individuals can increase their understanding of surgical and procedural processes and improve their familiarity with the tools utilized . The research team within Children ’ s Colorado ' s catheterization laboratory has been working on VR technologies for the last three years . In this research study , they aim to evaluate the role of VR for procedural planning in four specific scenarios .
Korean Institute of Advanced Technology
Grant type : Performance Partnership Grant ( PPG )
Title : “ Advancement of Customized Cardiac / Cardiovascular Surgical Solutions Based on 3D Printing and Advanced Imaging ”
The Korean Institute of Advanced Technology , or KIAT , is South Korea ’ s equivalent of the NIH . This project is a subproject of a larger one involving several departments within the University of Colorado system , of which radiologist Alex Barker , PhD , is the lead . Dr . Zablah is the primary investigator of the funded subproject . The funding is for $ 700k over four years out of approximately $ 2.1M in total available funding for the U . S . execution site . This project includes collaboration with academic and industry partners in South Korea ). The project ’ s objective is to support Children ’ s Colorado ’ s efforts to perform patient-specific surgical planning using imaging and 3D printing .
2023 Annual Report
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