Forum for Nordic Dermato-Venereology Nr2,2017 | Page 19

Anders Vahlquist– News from Acta Dermato-Venereologica – With Special Emphasis on Contributions from the Nordic Countries
Histidine decarboxylase (HDC) is the enzyme that catalyzes the synthesis of histamine. Recently,
an increase in epidermal HDC was shown in acute and chronic itch-related behaviors induced by
topical application of anionic surfactants in mice. We previously identified a colony of Cynomo-
lgus macaques (Macaca fascicularis) suffering from idiopathic chronic itch. In the present study,
we show that epidermal HDC is associated with itch severity in the primate model...
Pages: 739-740
Fig. 2. Editor’s choices in issues 6–8, vol 97 as displayed on the ActaDV website.
Forum for Nord Derm Ven 2017, Vol. 22, No. 2
A cta DV N ews
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