Forum for Nordic Dermato-Venereology Nr 3, 2018 | Page 11
Anette Bygum – Establishing a Clinical Trial Unit in Dermato-Venereology at Odense University Hospital, Denmark
health behaviour, treatment needs and quality of life in Danish
patients with hyperhidrosis. Our department is until now the
only public hospital offering microwave therapy for axillary
hyperhidrosis. A substudy will be performed using exome
sequencing to identify genes related to familial hyperhidrosis.
References
1. Hansen J. Ukontrollerbar sved – en overset sygdom. Sygeplejersken
2018, web article.
2. Kristiansen BH, Lindahl KH, Pallesen KAU, Bygum A. Two patients
with localised hyperhidrosis of the hand based on functional and
structural abnormalities of sweat glands. BMJ Case Rep 2018 Jan
31;2018. pii: bcr-2017-222530.
Pyoderma gangrenosum
Painful immunological ulcers, especially pyoderma gangreno-
sum, is a focus area among our nurse specialists. Two studies
have been established. A qualitative study of individual inter-
views looks into how the lifeworld of patients with pyoderma
gangrenosum is experienced. A Wound-QoL questionnaire has
been translated and is planned to be used in an upcoming
study of topical cannabinoids to pyoderma gangrenosum.
References
1. Knudsen JT, Hansen JM. Pyoderma gangrenosum – et smertensbarn.
SÅR, årgang 26, nr. 3, 2017.
2. Knudsen JT. Livskvalitetsskema (Wound-Qol) i sundhedsvæsenet.
SÅR, årgang 27, nr. 1, 2018.
Fig. 7. Teledermoscopy using smartphone and Handyscope®
for the treatment of basal cell carcinoma is presently being
undertaken in collaboration with our Adjunct Associate Pro-
fessor Maja Hofmann, Department of Dermatology, Charite
University Hospital, Berlin. Also the use of teledermoscopy
in primary care practice for the evaluation of skin cancer is
being studied (Fig. 7).
Reference
Epidermal detachment
The department is treating patients with severe bullous condi-
tions, including Stevens-Johnson syndrome, toxic epidermal
necrolysis and their overlap. A study is being conducted to
test a special wound dressing for these patients.
1. Broesby-Olsen S, Farkas DK, Vestergaard H, Hermann AP, Møller
MB, Mortz CG, et al. Risk of solid cancer, cardiovascular disease,
anaphylaxis, osteoporosis and fractures in patients with systemic
mastocytosis: A nationwide population-based study. Am J Hematol
2016; 91: 1069–1075.
Upcoming areas
Skin cancer and Teledermoscopy
The department has a large clinic for pigmented lesions and
skin cancer with 3-4 parallel outpatient clinics daily. All kid-
ney-transplant recipients and other solid organ transplant
recipients from the Region of Southern Denmark are offered
regular follow-up. Patients at high risk of developing melano-
ma are monitored with total body photography and sequential
digital dermoscopy. In cases of hereditary disorders, such as
Gorlin Goltz syndrome, the patients will be registered in a
genodermatosis database.
Also, the departments cohort of mastocytosis patients are
evaluated for skin cancer, as an increased risk of melanoma
has been reported. A clinical study on the use of CO 2 -laser
Forum for Nord Derm Ven 2018, Vol. 23, No. 3
As a strategic venture and with help from our Adjunct Pro-
fessor Steven Feldman and key persons at Sygehus Lillebaelt,
OUH and SDU, we would like to explore the field of patient
communication and narrative medicine in order to improve
patients’ satisfaction with care. The first ideas are born, and
we are working on protocols and applications for funding.
We hope, that the readers of Nordic Forum have got an impression
of our dermatologic department and research. We welcome you
to visit Odense and OUH and are open for new collaborations.
In order to facilitate the internationalization of clinical and
research environments, we have an International Staff Office
that provides help with legal, practical, social and cultural
issues, if people want to relocate to Denmark.
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