Ann-Kristin Björk – Patch Testing with Metals with Focus on Gold
Findings
In study I the reproducibility in patch testing did not differ on the back, however as the reactivity decreased so did reproducibility.
In study II it was shown that gold can be released to the skin when in prolonged contact, and the release increases with time.
Study III aimed at finding clinical relevance of contact allergy, especially to gold, in patients with lichen sclerosus. No association was found.
Study IV aimed at improving our knowledge on contact allergy to gold in general and possible associations with basic characteristics of the patients such as atopy, sex and age. In
the study there was an association between gold-allergy, age, sex, atopy and facial dermatitis.
List of publications
I. Björk A-K, Bruze M, Engfeldt M, Nielsen Ch, Svedman C. The reactivity of the back revisited. Contact Dermatitis 2016 Sep 4. doi: 10.1111 / cod. 12657. [ Epub ahead of print ]
II. Björk A-K, Bruze M, Engfeldt M, Persson L, Lundh T, Svedman C. How much metal is released to the skin during prolonged occlusion of gold objects? Submitted Contact Dermatitis.
III. Björk A-K, Svedman C, Asplund H, Lingärde S, Hindsén M, Hradil E, Bruze M. Contact allergy and vulvar lichen sclerosus et atrophicus. Immunome Res 2014: 10: 2.
IV. Björk A-K, Bruze M, Edman B, Engfeldt M, Björk J, Lövkvist H, Isaksson M, Pontén A, Svedman C. What can be learnt from patch testing with gold? A retrospective analysis of consecutive data from 1995 to 2014. In manuscript.
Permanent Hair Dyes. Exposure, Diagnostics, and Prevention of Contact Allergy
Annarita Antelmi, MD, PhD Department of Occupational and Environmental Dermatology, Skåne University Hospital, SE-214 21 Malmö, Sweden. E-mail: annarita. antelmi @ med. lu. se
Annarita Antelmi, defended on March 10, 2017 her doctoral thesis“ Permanent hair dyes. Exposure, diagnostics, and prevention of contact allergy”. Doctoral dissertation series; 2017:34, 2017. Lund. Available from: https:// lucris. lub. lu. se / ws / files / 21393336 / 2017.02.02 _ Thesis _ AA. pdf
The most frequently reported allergens in permanent hair dyes are PPD, 2,5-TDA or 2,5-TDA-S, both categorized as strong skin sensitizers. Recently a new hair dye substance, 2-ME-PPD was introduced with the aim is to decrease the risk of allergic contact dermatitis. PPD is most common in hair dye product sold in central and southern Europe and in non-European countries, while 2,5-TDA-S is more prevalent in northern Europe. Products purchased in Europe and analysed of their content of PPD and 2,5-TDA, never exceeded the limits stated by the European legislation.
Products bought in non-European countries contained higher PPD concentrations and sometimes exceeding the limits of the EC. Hair dyes products can be incorrectly labelled. In spite of the limits of concentrations stated by the EC on permanent hair dyes ingredients, products purchased on Internet or outside Europe can expose consumers and hairdressers to high concentrations of strong contact allergens.
Hairdressers have a high risk to develop hand dermatitis why it is important that they adopt correct preventive strategies as choosing the optimal protective gloves. When considering the diagnostics of contact allergy to permanent hair dyes, PPD 1.0 % in pet. is a better tracer than 2,5-TDA although 2,5-TDA is more
Annarita Antelmi with Professor Giorgio Assennato( Opponent), Emeritus of Environmental and Occupational Medicine, Department of Biology, University of Bari, Italy to the left and Associate Professor Cecilia Svedman( Main Supervisor), Department of Occupational and Environmental Dermatology, Lund University, Malmö, to the right.
20 Dissertation
Forum for Nord Derm Ven 2018, Vol. 23, No. 1