Baylor University Medical Center Proceedings April 2014, Volume 27, Number 2 | Page 21

MS is not the gold standard for cardiovascular risk, as evidenced by the fact that morbidity and mortality are high in Black and Hispanic Americans and lower in women (8–10). As noted elsewhere, genetic, nutritional, and environmental factors that influence the expression of MS and promote and suppress the expression of full-blown heart disease, coronary heart disease, and congestive heart disease are essential in the expression of disease (12–15). It is important to acknowledge MS as a precursor to cardiovascular risk that can be addressed in primary prevention efforts. Evidence of a decline in MS achieved in wellness programs is an indicator of interventional success; smoking cessation, weight loss, loss of abdominal girth, and change in eating patterns are some strategies that can be used to mitigate inherited factors. The interplay of MS with genetic and behavioral factors on the risk for cardiovascular disease should be explored in future studies. 1. 2. 3. 4. 5. Yoon YS, Lee ES, Park C, Lee S, Oh SW. The new definition of metabolic syndrome by the International Diabetes Federation is less likely to identify metabolically abnormal but non-obese individuals than the definition by the revised National Cholesterol Education Program: the Korea NHANES study. Int J Obes (Lond) 2007;31(3):528–534. Palaniappan LP, Wong EC, Shin JJ, Fortmann SP, Lauderdale DS. Asian Americans have greater prevalence of metabolic syndrome despite lower body mass index. Int J Obes (Lond) 2011;35(3):393–400. Riediger ND, Clara I. Prevalence of metabolic syndrome in the Canadian adult population. CMAJ 2011;183(15):E1127–1134. Papoutsakis C, Yannakoulia M, Ntalla I, Dedoussis GV. Metabolic syndrome in a Mediterranean pediatric cohort: prevalence using International Diabetes Federation-derived criteria and associations with adiponectin and leptin. Metabolism 2012;61(2):140–145. Fitzpatrick SL, Lai BS, Brancati FL, Golden SH, Hill-Briggs F. Metabolic syndrome risk profiles among African American adolescents: National Health and Nutrition Examination Survey, 2003–2010. Diabetes Care 2013;36(2):436–442. April 2014 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Haffner SM, D’Agostino R, Saad MF, Rewers M, Mykkänen L, Selby J, Howard G, Savage PJ, Hamman RF, Wagenknecht LE, Bergman RN. Increased insulin resistance and insulin secretion in nondiabetic AfricanAmericans and Hispanics compared with non-Hispanic whites. The Insulin Resistance Atherosclerosis Study. Diabetes 1996;45(6):742–748. Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA 2002;287(3):356–359. Ervin RB. Prevalence of metabolic syndrome among adults 20 years of age and over, by sex, age, race and ethnicity, and body mass index: United States, 2003–2006. Natl Health Stat Report 2009;(13):1–7. Su C, Fan r2