VISIBLE ACNE LESION REDUCTION AS EARLY AS WEEK 1 WITHOUT AN ANTIBIOTIC * 1
Clinically proven to:* 1
Reduce total acne lesions by
70
Reduce acne scarring by more than 55
% % in 24 weeks
5.8 % incidence of treatment-emergent adverse events. The most common event(> 1 %) was skin tightness( 1.7 %), and all events were mild to moderate.* 1
TREAT | REDUCE | PREVENT
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AKLIEF( trifarotene 50 µ g / g) Cream is indicated for the topical treatment of acne vulgaris of the face and / or the trunk in patients from 12 years of age and older, when many comedones, papules and / or pustules are present. 2
* Results from a randomised, split-face, double-blind study of patients aged 17 – 34 years( N = 121) with moderate-to-severe facial acne and acne scars treated with AKLIEF Cream or vehicle once daily for 24 weeks. At Week 1, the reduction in total acne lesion counts from baseline was significantly greater with AKLIEF Cream vs vehicle( P = 0.0097). At Week 24, the percentage reduction in mean total acne lesion count was 70.0 %( from baseline: 37.3) with AKLIEF Cream vs 44.9 %( from baseline: 37.3) with vehicle( nominal P < 0.05), and the reduction in total atrophic acne scar count was 5.9 from baseline with AKLIEF Cream vs 2.7 with vehicle( P < 0.0001, primary endpoint). 1
The START clinical trial was sponsored by Galderma. 1 References: 1. Schleicher S et al. Dermatol Ther( Heidelb) 2023; 13( 12): 3085 – 3096. 2. AKLIEF( trifarotene 50 µ g / g) Cream Product Information.
This medicinal product is subject to additional monitoring. This will allow quick identification of new safety information. Healthcare professionals are asked to report any suspected adverse reactions.
PBS Information: AKLIEF( trifarotene 50 µ g / g) Cream is not listed on the PBS.
Please review the full Product Information before prescribing, available on request from Galderma Medical Information on 1800 800 765, at galderma. com / au / sites / default / files / Aklief _ PI _ 181124. pdf or by scanning the QR code.
Galderma Australia Pty Ltd. Level 18, 1 Denison Street, North Sydney 2060. ABN 12 003 976 930. Galderma and AKLIEF ® are registered trademarks of Galderma Holding S. A. AU-AFC-2500067. AKL-005225-00. SSW. Date of preparation: July 2025.