inflammation , 10 , 18 vascular inflammation , 8 neurogenic inflammation , 10 oxidative stress , 16 development of scarring and adhesions , 18 fatigue , 18 stress , 12 , 19 chronic stress , 19 peripheral sensitisation , central sensitisation , and enhanced pelvic nociception . 10 The intensity of stress correlates with pain severity and severity of endometriosis : 19 the more severe the endometriosis is , the more severe the pain suffered . Endometriosis is the most common cause of chronic pelvic pain . 11 Chronic pain frequently returns in patients within 12 months of removal of lesions , even in the absence of lesion regeneration . 10 It is noted that pain is a multidimensional experience that involves sensory , cognitive , and affective factors . 20 Infertility is experienced by around 30-50 % of women with endometriosis . 5 , 21 Endometriosis has a significant negative impact on the lives
18 , 22 of women .
Magnesium
Optimum nutrition is the foundation for optimum health . 13 Magnesium is an important mineral for normal biological function . 23 It is involved in over 300 enzyme reactions . 24 Magnesium plays an important physiological role , particularly in the brain , heart , and skeletal muscles . 25 It is involved in the synthesis of adenosine triphosphate ( ATP ), DNA , and RNA , 24 , 26 mitochondrial health , 27 utilisation of intracellular energy , 26 relaxation of smooth muscle , 8 normal muscle function , 27 neurotransmission , 27
23 , 26 neuromuscular transmission , parathyroid hormone metabolism , 26 metabolism of carbohydrates , protein and fats , 26 and nitric oxide metabolism . 27 Magnesium is involved in the maintenance of cell membrane function and the sodium-potassium gradient across all membranes , 26 regulation of intracellular calcium levels , 26 normal nerve function , neurotransmitters , bone
strength , 27 heart rhythm , 26 , 27 vasomotor tone , 26 and the immune system . 27
Research has found that the fallopian tubes of women with endometriosis do not contract at regular intervals but more spasmodically and in waves . 28 Magnesium has been shown to relax smooth muscles 8 and may be useful in relaxing the spasms and waves of muscle contraction during this time .
A deficiency of magnesium has been
24 , 26 , 27 associated with muscle spasms , muscle cramping , 26 , 27 muscle twitches , 26 muscle weakness , 26 neuromuscular hyperexcitability , 29 , 30 numbness , tingling , 27 nervousness , 27 24 , 26
anxiety , apathy , depression , agitation , 26 and decreased gut motility . 26 Additionally , magnesium deficiency has been associated with cardiovascular diseases , 24 , 31 altered glucose homeostasis , 30 24 , 31 type 2 diabetes ,
Calm mind , focused brain .
KeenMind has been specifi cally developed to support learning , memory and concentration in times of stress . Not only does it provide calm , clear focus , but evidence shows it can reduce nervous tension and mild anxiety too .
Recommend KeenMind to support learning , memory & calm focus
COMPLIMENTARY WEBINAR SERIES : Expert Prof Con Stough on CDRI 08 and cognition .
Visit flordis . com . au / health-professionals /
HEALTH PROFESSIONAL ONLY