ASC Treatment Brochure V1 | Page 15

*OOPWBUJWF4UFN$FMM4PMVUJPOT Safety The nature of the stem cells necessitate ample safety standards. ASC Treatment has multiple safety standards in place to mitigate any operational risks. • Vero Insurance Each treatment procedure is also insured by Vero Insurance, one of Australia’s most prominent medical insurers for up to AUD 20 million. This is also the only stem cell treatment within Australia to be covered by a medical insurance policy, reflecting high safety profile of AMPC. Your peace of mind will be ensured with our stem cell treatments. • Non-genetic manipulation culture The method of stem cell culture does not involve genetic manipulation that may result in a risk of mutation that contributes to cancer. No viruses, antibiotics, growth factors, animal components, or reagents are added into the culture of the stem cells. • Regulation-compliant laboratories All culture processes take place in ASC’s laboratories. The current facilities include a physical containment 2 laboratory and all protocols are compliant with Good Tissue Practice (GTP). • Autologous The autologous nature of the cells also removes many risks associated with transplantation of cells foreign to the body. These cells are sourced from the recipient’s body that recognises the physiology, and will thus easily be reintegrated into the system. • Closed system culture The collected blood is sealed in the blood bag and all subsequent processes take place within a closed system until the day of reinfusion. All tubes and connections to the blood bag are sealed with high heat with a Terumo docking station that sterilises the sealed point. Spiking will also be done to retrieve a small sample for screening. This process takes place under a laminar flow cabinet to prevent contamination. • NATA screening To further ensure sample safety, each cultured sample is screened by a NATA-accredited laboratory for contamination. The tests screen for total viable aerobic count, total viable count, microbial growth, endotoxin, and real-time PCR mycoplasma tests. These ensure that the live cells are not contaminated. • Preclinical safety test and safety trials The product has undergone extensive pre-clinical testing and is now embarking on safety trials further verify safety, as per the standards set by the International Society for Stem Cell Research (ISSCR). Disclaimer Although stem cell therapy has been demonstrated to alleviate symptoms of different disorders, it can neither predict nor guarantee the success of every stem cell therapy procedure. This is due to the nature of all medical interventions where there is an inherent risk attached. A medical practitioner should be consulted should there be any concerns with partaking in this treatment. "650-0(06445&.$&--53&"5.&/5 13