Annual Review 2018 | Page 27

Quality of patient-ventilator interaction in Southeast Asia intensive care Mechanical ventilation is used in intensive care to treat patients suffering from respiratory failure, but it can damage the lungs when not optimised. Current clinical practice lacks a practical method to determine patient-specific ventilation settings. To address this issue, a decision support system (Clinical Application of Respiratory Elastance: CARE) is currently being tested in Malaysia. It can be used in conjunction with readily available bedside data to optimise treatment. This research is developing a data acquisition system for mechanical ventilators in hospital intensive care units, and conducting clinical trials to investigate the quality of patient-ventilator interaction. Researchers: Dr Chiew Yeong Shiong and Associate Professor Tan Chee Pin Funding agency: Medical Technologies Centre of Research Excellence (Medtech Core) Tunable band-edge potential and electronic band structure for semiconductor photocatalysts for efficient carbon dioxide photoreduction and photocatalytic water splitting Increasing demands for energy have prompted researchers from around the world to aim to mimic natural photosynthesis by coupling photocatalytic water splitting and carbon dioxide photoreduction to produce sustainable fuels and, at the same time, reduce global carbon dioxide levels. Advancements in the artificial photosynthetic system not only alleviate global climate change, but also reduce dependency on conventional fossil fuels. However, constructing an artificial mechanism is a challenging task and requires a highly efficient photocatalyst that is able to perform both reactions. This study is focussed on the development of unique two-dimensional semiconductor photocatalysts with tunable band structure for enhanced carbon dioxide reduction as well as water splitting. Mapping the biodiversity and abundance of Usnea for environmental conservation planning Lichens are serving a critical role as ideal ecological indicators that reflect the true local conditions of an area. A cost- and time-efficient means, these organisms have been successfully utilised in monitoring air pollution and climate change in Antarctica. This research is identifying different species of the lichen Usnea within Peninsular Malaysia and mapping geographic patterns based on their distribution. Assessment of probable environmental risk of each collection site, based on the abundance and distribution of the collected lichens, will also be performed. Researcher: Krystle Angelique Aguda Santiago Funding agency: Nagao Natural Environment Foundation Researcher: Professor Chai Siang Piao, Dr Chang Wei Sea and a co-researcher from Universiti Sains Malaysia Funding agency: Ministry of Education (for Prof Chai’s Malaysia Research Star Award 2017) AI alloy electrode quartz crystal microbalance for wearable sensor applications Recent advancements have catalysed the growth of wearable device technologies beyond smartwatches or fitness trackers. One such wearable device is an ultraviolet (UV) sensor capable of measuring UV index and informing users to protect themselves from excessive sunlight UV exposure. However, there are several challenges in terms of sensitivity, response time, repeatability, power consumption, and wide-angle sensing features. Over the past few years, research on devising acoustic wave-based UV sensors has been ongoing. In a recent development, quartz crystal microbalance (QCM) was utilised as a UV sensor and demonstrated its suitability for wearable applications. A wearable UV sensor prototype was developed to overcome some of the challenges and stands as an example of a wearable device that uses QCM for sensing applications. Researchers: Dr Narayanan Ramakrishnan, Dr Tridib Saha and Dr Ajay Achath Mohanam Funding agency: Piezo Parts Co Ltd, Japan 26