Acta Dermato-Venereologica 99-9CompleteContent | Page 26

837 Yellowish Nodules on the Vulva in a 6-year-old Girl: A Quiz Marianela ACKERMAN 1 , Annabel MARUANI 2 , Eric ESTEVE 1 , Remy KERDRAON 3 and Antoine FINON 1 Departments of 1 Dermatology and 3 Pathology, CHR Orleans, FR-45000 Orléans, and 2 Department of Dermatology, University of Tours, CHRU Tours, Tours, France. E-mail: [email protected] A 6-year-old girl with no significant medical history and who was not undergoing treatment, presented a 5-month history of multiple, scattered, asymptomatic, yellowish papulo-nodules with soft-elastic consistency in the vulva. Multiple, slightly papular, brownish plaques were on the inner side of her thighs and upper part of the back and neck (Fig. 1). Darier’s sign was negative for all lesions. Complete physical examination revealed no other anomaly, no other systemic complaints were present, and laboratory findings were normal. A skin biopsy of a nodule was performed (Fig. 2). Fig. 1. (A) Nodules on the vulva and plaque on the thigh. (B) Plaques on the neck. What is your diagnosis? See next page for answer. Fig. 2. (A) Haematoxylin-eosin staining 50×: deep and dense cellular infiltrate in dermis. (B) Giemsa staining 400×. (C) CD117 immunochemistry 25×. QUIZ SECTION This is an open access article under the CC BY-NC license. www.medicaljournals.se/acta Journal Compilation © 2019 Acta Dermato-Venereologica. doi: 10.2340/00015555-3204 Acta Derm Venereol 2019; 99: 837–838