ACE Issue 24 2019 | Page 40

Robotics lead to faster discoveries for microbiologists M itsubishi Electric has supported Peak Analysis & Automation (PAA) in the delivery of an innovative, fully automated laboratory workcell for bacteriological studies to the U.S. Department of Commerce’s National Institute of Standards and Technology (NIST). The application is built around a Mitsubishi Electric MELFA articulated arm robot with its own proximity-based safety solution. Scientists at NIST can now benefit from a flexible and reliable system to perform several bacterial growth tests in parallel, significantly shortening discovery times and reducing the risk of contamination. The S-CEL™ Robotic System is a fully integrated, modular and customisable workcell that can accommodate a broad range of devices to meet different research requirements. NIST is a science and technology laboratory whose research efforts include developing and promoting common guidelines, practices and standards for industry, public bodies and academia. Its purpose is to drive U.S. innovation and competitiveness. The automated laboratory from Mitsubishi Electric and PAA provides specific environmental conditions for the proliferation of studied organisms whilst also avoiding sample contamination. Automated solutions act as a breeding ground for innovation As a global leader in laboratory automation for life sciences, PAA offers a cutting-edge solution that supports optimal testing and measurement. The company provided one of their flexible solutions, the S-CEL™ Robotic System, which is a fully integrated, modular and customisable workcell that can accommodate a broad range of devices to meet different research requirements. By using automated process technology, scientists can avoid tedious and repetitive tasks and concentrate on analysing laboratory data. For this specific application, NIST and PAA planned a system that would automatically prepare culture media for bacteria, manipulate the organisms’ 40 Images: Peak Analysis and Automation (PAA) DNA and measure their growth rates as well as any underlying patterns. The workcell features a laminar clean air system that flushes away airborne contaminants and protects the biological samples and equipment within the unit from contamination. Once inside, the S-CEL™ system is comprised of devices to store the microtiter plates, where the microbes are cultivated, as well as plate readers and incubators to monitor bacterial growth in set conditions. In order to modify the organisms, the unit also enables a nuclear vector transfer function for genetic material. Other key components include liquid handlers for pouring growth media substrates into the plates, plate sealers and peelers that cover or remove seals and lids from the microtiter plates, as well as temperature-controlled centrifuges to spin samples when required. All these instruments, located around the workcell, required an automated pick and place solution, to move samples and consumables around the different stations to perform all the relevant tasks without any human intervention.