53
EVENT FORMAT
Lecture
2020
Januar y
12-2 3
Transcriptional Control of Neuronal Identity
DESCRIPTION
Using C. Elegans as a model system, they have revealed the regulatory mechanisms that control terminal neuronal
identity and demonstrated that these mechanisms are conserved in chordates. They also used this knowledge to re-
program the identity of heterologous cell types to become specific neuron types. The lab’s other interests include the
origins of asymmetrical neuronal differentiation along the left/right axis, the molecular mechanisms of neural system
plasticity, and the conservation and evolution of neuronal gene expression programs. His lab has also developed a
number of tools to analyze whole-genome sequence data.
SPEAKER Oliver Hobert
CREDITS 1
Professor of Biochemistry and Molecular Biophysics at Columbia University and
Investigator of the Howard Hughes Medical Institute
Oliver Hobert is a Professor in the Columbia University Department of Biochemistry and Molecular Biophysics and an
Investigator of the Howard Hughes Medical Institute and holds an Interdisciplinary Faculty position in the Department
of Systems Biology. His laboratory studies the molecular mechanisms responsible for generating the remarkable
diversity of cell types found in the nervous system.