43
EVENT FORMAT
Lecture
2020
Januar y
12-2 3
Bioresponsive Smart Drug Delivery
DESCRIPTION
In this talk, Professor Gu will discuss their ongoing efforts in developing physiological signal-triggered bioinspired
drug delivery systems. He will first present the glucose-responsive synthetic systems for biomimetic delivery of insu-
lin for diabetes treatment. Bioresponsive microneedle patches and vesicle fusion-mediated synthetic beta cells will
be emphasized. He will further discuss the local and targeted delivery of immunomodulatory therapeutics for en-
hanced cancer therapy. His latest study utilizing platelets, cell conjugates and gels for delivery of immune checkpoint
inhibitors will be specifically introduced.
SPEAKER Zhen Gu
CREDITS 1
Professor in the Department of Bioengineering and Director of the NIH Biotechnology
Training in Biomedical Sciences and Engineering Program at UCLA
Spurred by recent advances in materials chemistry, molecular pharmaceutics, and nanobiotechnology,
stimuli-responsive “smart” systems offer opportunities for precisely delivering drugs in dose-, spatial- and
temporal-controlled manners.