CONTENTS
1 Surviving in a Microbial World, 1 2 Innate Immunity: How to Detect Invaders, 8 3 Humoral Innate Immunity: Inflammation, 17 4 Humoral Innate Immunity: Antimicrobial Peptides, 25 5 Humoral Innate Immunity: The Complement System, 31 6 Cellular Innate Immunity: Leukocytes, 43 7 Cellular Innate Immunity: Macrophages and Recovery from
Inflammation, 54 8 Sickness: The Body ' s Innate Responses, 64 9 How Immune Cells Communicate: Cytokines and Their
Receptors, 75 10 Antigens: Triggers of Adaptive Immunity, 85 11 Dendritic Cells, Antigen Processing, and Presentation, 91 12 The Major Histocompatibility Complex, 101 13 Lymphoid Organs: Their Structure and Functions, 109 14 Lymphocytes, 123 15 Helper T Cells: Diverse Responses to Antigens, 133 16 B Cells and Their Response to Antigens, 149 17 Antibodies: Soluble Antigen Receptors, 162 18 How Antigen-Binding Receptors Are Made, 174 19 T Cells and the Destruction of Intracellular Invaders, 187 20 Innate Lymphoid Cells, 199 21 Regulation of Adaptive Immunity, 210 22 The Microbiota and the Immune System, 221 23 Immunity on Body Surfaces, 233 24 Immunity in the Fetus and Newborn, 246 25 Vaccines and Their Production, 259
26 |
The Use of Vaccines, 272 |
27 |
Immunity to Bacteria and Fungi, 282 |
28 |
Immunity to Viruses, 293 |
29 |
Immunity to Parasites, 306 |
30 |
Mast Cell— and Eosinophil-Mediated Hypersensitivity, 322 |
31 |
Selected Allergic Diseases, 334 |
32 Red Cell Antigens and Antibody-Mediated Hypersensitivity, |
346 |
33 Immune Complexes and Neutrophil-Mediated |
Hypersensitivity, 355 |
34 |
T Cell-Mediated Hypersensitivities, 366 |
35 |
Organ Graft Rejection and Pregnancy, 376 |
36 |
Tumor Immunology and Immunotherapy, 387 |
37 |
Autoimmune Diseases and the Loss of Tolerance, 401 |
38 |
Selected Organ-Specific Autoimmune Diseases, 408 |
39 Selected Immune-Mediated Inflammatory Diseases, 419 |
40 |
Primary Immunodeficiency Diseases, 430 |
41 |
Secondary Immunological Defects, 443 |
42 Drugs and Other Agents That Affect the Immune System, |
456 |
43 |
Immunodiagnostic Methods, 466 |
Appendix 1: Selected CD Molecules, 485
Appendix 2: Some Selected Cytokines, 487 Appendix 3: Some Important Abbreviations, 491 Glossary, 493
Index, 499