Vet360 Issue 4 Volume 2 | Page 27

DERMATOLOGY Article reprinted with the permission of Clinician’s Brief. The article was originally printed in August 2013 CB is published by Brief Media. CB is the official publication of the NAVC. CB provides relevant diagnostic and treatment information for small animal practitioners. All rights reserved. Canine Peri-oral Dermatitis Jennifer Schissler Pendergraft, DVM, MS, DACVD Colorado State University Profile Definition • Peri-oral dermatitis (PD) is inflammation of the maxillary or mandibular cutaneous or mucocutaneous tissues. • PD has diverse clinical presentations and causes and may be noted as a singular clinical entity or among generalized dermatologic or systemic signs. Systems • • PD is not limited to lip fold intertrigo (ie, bacterial and Malassezia spp overgrowth; (Figure 1); rather, it is a potential manifestation of focal or generalised cutaneous conditions. Conditions include hypersensitivities, immunemediated dermatopathy, infection, hepatopathy, periodontal disease, and neoplasia. Figure 1: Lip fold intertrigo in a dog Signalment & Causes Some causes have known breed and age associations. Risk Factors • • • • Redundant lip folds can predispose patients to intertrigo. Any primary cause of PD poses risk for secondary bacterial or Malassezia spp infection. Chronic use of topical or systemic glucocorticoids poses risk for demodicosis. Sun exposure can pose a risk for pemphigus foliaceus and discoid lupus erythematosus (Figure 2). Pathophysiology • • • Figure 2: Discoid lupus erythematosus in a dog Cutaneous or mucocutaneous inflammation can occur from causes that prompt erythema, pruritus, and primary lesions (eg, papules, pustules, vesicles, bullae), followed by secondary lesions (eg, erosions, ulcerations, crusts, alopecia). The resulting skin barrier disruption predisposes patients to secondary bacterial and Malassezia spp overgrowth. The micro-environment of a deep, redundant lip Figure 3: Zinc-responsive dermatitis in a dog • • fold predisposes patients to intertrigo. Severe periodontal disease with ptyalism may predispose to secondary perioral infection, particularly with deep lip folds. Pruritus and malodour are common. Issue 04 | JULY 2015 | 27